R
Roger Schneiter
Researcher at University of Fribourg
Publications - 118
Citations - 8466
Roger Schneiter is an academic researcher from University of Fribourg. The author has contributed to research in topics: Lipid droplet & Endoplasmic reticulum. The author has an hindex of 40, co-authored 109 publications receiving 7608 citations. Previous affiliations of Roger Schneiter include University of Freiburg & University of Graz.
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Journal ArticleDOI
Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane.
Tomomi Kuwana,Mason R. Mackey,Guy Perkins,Mark H. Ellisman,Martin Latterich,Roger Schneiter,Douglas R. Green,Donald D. Newmeyer +7 more
TL;DR: It is concluded that mitochondrial protein release in apoptosis can be mediated by supramolecular openings in the outer mitochondrial membrane, promoted by BH3/Bax/lipid interaction and directly inhibited by Bcl-x(L).
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Lipid signalling in disease
TL;DR: A more integrated overview of the key role of these signalling lipids in inflammation, cancer and metabolic disease is attempted, and emerging strategies for therapeutic intervention are discussed.
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Electrospray Ionization Tandem Mass Spectrometry (Esi-Ms/Ms) Analysis of the Lipid Molecular Species Composition of Yeast Subcellular Membranes Reveals Acyl Chain-Based Sorting/Remodeling of Distinct Molecular Species En Route to the Plasma Membrane
Roger Schneiter,Britta Brügger,Roger Sandhoff,Guenther Zellnig,Andrea Leber,Manfred Lampl,Karin Athenstaedt,Claudia Hrastnik,Sandra Eder,Günther Daum,Friedrich Paltauf,Felix T. Wieland,Sepp-Dieter Kohlwein +12 more
TL;DR: The accumulation of monounsaturated species of PS at the expense of diunsaturated species in the plasma membrane of wild-type cells was reversed in elo3Δ mutant cells, which synthesize C24 fatty acid-substituted sphingolipids instead of the normal C26 fatty acid
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Lipid droplets are functionally connected to the endoplasmic reticulum in Saccharomyces cerevisiae.
Nicolas Jacquier,Vineet Choudhary,Muriel Mari,Alexandre Toulmay,Fulvio Reggiori,Roger Schneiter +5 more
TL;DR: Photobleaching experiments (FRAP) indicate that relocation of membrane proteins from the ER to LDs is independent of temperature and energy, and thus not mediated by classical vesicular transport routes.
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Roles of Phosphatidylethanolamine and of Its Several Biosynthetic Pathways in Saccharomyces cerevisiae
TL;DR: Three different pathways lead to the synthesis of phosphatidylethanolamine (PtdEtn) in yeast, one of which is localized to the inner mitochondrial membrane, and a series of deletion mutants in which different combinations of the pathways are blocked showed an enhanced formation of respiration-deficient cells.