R
Rohini Kuner
Researcher at Heidelberg University
Publications - 172
Citations - 10071
Rohini Kuner is an academic researcher from Heidelberg University. The author has contributed to research in topics: Nociception & Chronic pain. The author has an hindex of 51, co-authored 148 publications receiving 8068 citations. Previous affiliations of Rohini Kuner include Molecular Medicine Partnership Unit.
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Journal ArticleDOI
Neuron-specific biomarkers predict hypo- and hyperalgesia in individuals with diabetic peripheral neuropathy.
Jakob Morgenstern,Jan B. Groener,Johann M E Jende,Felix T. Kurz,Alexander Strom,Jens C. Göpfert,Zoltan Kender,Maxime Le Marois,Maik Brune,Rohini Kuner,Stephan Herzig,Michael Roden,Dan Ziegler,Martin Bendszus,Julia Szendroedi,Peter P. Nawroth,Stefan Kopf,Thomas Fleming +17 more
TL;DR: In this paper, the authors investigated myelin-specific circulating mRNA targets, which have been identified in vitro, for their capacity in the diagnosis and prediction of diabetic neuropathy, and the most promising candidate was tested against the recently established biomarker of neural damage, neurofilament light chain protein.
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Loss of POMC-mediated antinociception contributes to painful diabetic neuropathy.
Divija Deshpande,Divija Deshpande,Nitin Agarwal,Thomas Fleming,Claire Gaveriaux-Ruff,Christoph S. N. Klose,Anke Tappe-Theodor,Rohini Kuner,Peter P. Nawroth +8 more
TL;DR: In this article, the antinociceptive pathway mediated by POMC is further impaired due to lysosomal degradation of μ-opioid receptor (MOR).
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Neurobiology of brain oscillations in acute and chronic pain.
TL;DR: This review addresses parallels between insights from human and rodent analyses of oscillatory rhythms in acute and chronic pain and discusses recent rodent-based studies that have shed light on mechanistic underpinnings of brain oscillatory dynamics in pain-related behaviors.
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Repetitive non-invasive prefrontal stimulation reverses neuropathic pain via neural remodelling in mice.
TL;DR: In this article, the potential of prefrontal tDCS for non-invasive, repetitive direct anodal current transcranial stimulation (tDCS) of the prefrontal cortex exerted analgesia in mice with chronic pain for longer than a week.
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A mouse model for pain and neuroplastic changes associated with pancreatic ductal adenocarcinoma.
TL;DR: An immunocompetent orthotopic mouse model of PDAC involving intrapancreatic growth of K8484 mouse PDAC cells is described, which reliably exhibits a large number of key characteristics of human PDAC, including its unique histopathology and neuroplastic changes.