R
Romina Gamberale
Researcher at Academia Nacional de Medicina
Publications - 55
Citations - 1791
Romina Gamberale is an academic researcher from Academia Nacional de Medicina. The author has contributed to research in topics: Chronic lymphocytic leukemia & Apoptosis. The author has an hindex of 19, co-authored 54 publications receiving 1628 citations. Previous affiliations of Romina Gamberale include University of Buenos Aires & New York Academy of Medicine.
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Journal Article
Extracellular Acidification Induces Human Neutrophil Activation
Analía Silvina Trevani,Graciela Andonegui,Mirta Giordano,Daniel H. Lopez,Romina Gamberale,Fernando Minucci,Jorge Geffner +6 more
TL;DR: The notion that extracellular acidosis may intensify acute inflammatory responses by inducing neutrophil activation as well as by delaying spontaneous apoptosis and extending neutrophils functional lifespan is supported.
Journal ArticleDOI
A critical role for Syk protein tyrosine kinase in Fc receptor-mediated antigen presentation and induction of dendritic cell maturation.
Christine Sedlik,Daniel Orbach,Philippe Veron,Edina Schweighoffer,Francesco Colucci,Romina Gamberale,Andrea Ioan-Facsinay,Sjef Verbeek,Paola Ricciardi-Castagnoli,Christian Bonnerot,Victor L. J. Tybulewicz,James P. Di Santo,Sebastian Amigorena +12 more
TL;DR: It is found that FcR engagement by immune complexes induced the phosphorylation of Syk, a protein tyrosine kinase acting immediately downstream of FcRs, which represents a novel pathway for the induction of DC maturation.
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Extracellular acidosis induces neutrophil activation by a mechanism dependent on activation of phosphatidylinositol 3-kinase/Akt and ERK pathways.
Diego Martínez,Mónica Vermeulen,Analía Silvina Trevani,Ana Ceballos,Juan Sabatté,Romina Gamberale,María E. Alvarez,Gabriela Salamone,Tamara Tanos,Omar A. Coso,Jorge Geffner +10 more
TL;DR: The results support the notion that the stimulation of human neutrophils by extracellular acidosis is dependent on the activation of PI3K/Akt and ERK pathways.
Journal ArticleDOI
Promotion of Neutrophil Apoptosis by TNF-α
Gabriela Salamone,Mirta Giordano,Analía Silvina Trevani,Romina Gamberale,Mónica Vermeulen,Jorge Schettinni,Jorge Geffner +6 more
TL;DR: The results suggest that TNF-α plays a critical role in the control of neutrophil survival by virtue of its ability to induce an apoptotic death program which could be triggered by a variety of conventional agonists.
Journal ArticleDOI
Control of dendritic cell differentiation by angiotensin II
Karen Nahmod,Mónica Vermeulen,Silvina Raiden,Gabriela Salamone,Romina Gamberale,Paula Fernández-Calotti,Azucena L. Alvarez,Victor E. Nahmod,Mirta Giordano,Jorge Geffner +9 more
TL;DR: The notion that the differentiation of DC is regulated by AII is supported by the findings that human monocytes produce angiotensin II and express AT1 and AT2 receptors for AII.