R
Ronald Abraham
Researcher at University of Texas MD Anderson Cancer Center
Publications - 9
Citations - 523
Ronald Abraham is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Gene & Comparative genomic hybridization. The author has an hindex of 6, co-authored 9 publications receiving 468 citations.
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Journal ArticleDOI
Association of MicroRNA Expression with Microsatellite Instability Status in Colorectal Adenocarcinoma
Jonathan S.L. Earle,Rajyalakshmi Luthra,Angela Romans,Ronald Abraham,Joe Ensor,Hui Yao,Stanley R. Hamilton +6 more
TL;DR: The findings indicate that miRNA expression in CRC is associated with MSI sub groups, including low MSI and HNPCC-associated cancers, and that miRNAs may have posttranscriptional gene regulatory roles in these MSI subgroups and possible effects on the clinicopathologic and biomarker characteristics.
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MicroRNA-196a Is a Potential Marker of Progression during Barrett's Metaplasia-Dysplasia-Invasive Adenocarcinoma Sequence in Esophagus
Dipen M. Maru,Rajesh R. Singh,Christina Hannah,Constance Albarracin,Yong Li,Ronald Abraham,Angela Romans,Hui Yao,Madan G. Luthra,Sharmila Anandasabapathy,Stephen G. Swisher,Wayne L. Hofstetter,Asif Rashid,Rajyalakshmi Luthra +13 more
TL;DR: This study evaluated the correlation of miR-196a with its in silico-predicted targets, keratin 5 (KRT5), small proline-rich protein 2C (SPRR2C), and S100 calcium-binding protein A9 (S100A9), which are down-regulated during BE progression.
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Clinical massively parallel next-generation sequencing analysis of 409 cancer-related genes for mutations and copy number variations in solid tumours.
Rakesh K. Singh,Keyur P. Patel,Mark J. Routbort,Kenneth Aldape,Xinyan Lu,Jawad Manekia,Ronald Abraham,Neelima Reddy,Bedia A. Barkoh,J Veliyathu,L. J. Medeiros,RP Luthra +11 more
TL;DR: The Ion Proton (409-gene panel) system was found to be well suited for use in a clinical molecular diagnostic laboratory and can simultaneously screen 409 genes for a variety of sequence variants in multiple samples using a low input of FFPE DNA with high reproducibility and sensitivity.
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Suppressed immune microenvironment and repertoire in brain metastases from patients with resected non-small-cell lung cancer
Y. Kudo,Y. Kudo,Cara Haymaker,J. Zhang,Alexandre Reuben,Dzifa Y. Duose,James G. Fujimoto,Sinchita Roy-Chowdhuri,L.M. Solis Soto,Hitoshi Dejima,Edwin R. Parra,Barbara Mino,Ronald Abraham,Norihiko Ikeda,A. Vaporcyan,Don L. Gibbons,Frederick F. Lang,Rajyalakshmi Luthra,J. Jack Lee,Cesar A. Moran,Jason T. Huse,Humam Kadara,I. I. Wistuba +22 more
TL;DR: Findings suggest that the TIME in brain metastases from NSCLC is immunosuppressed and comprises immune phenotypes that may help guide immunotherapeutic strategies for NSCLCs brain metastasis.
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Genome-wide copy number aberrations and HER2 and FGFR1 alterations in primary breast cancer by molecular inversion probe microarray.
Hui Chen,Rajesh R. Singh,Xinyan Lu,Lei Huo,Hui Yao,Kenneth Aldape,Kenneth Aldape,Ronald Abraham,Shumaila Virani,Meenakshi Mehrotra,Bal Mukund Mishra,Alex Bousamra,Alex Bousamra,Constance Albarracin,Yun Wu,Sinchita Roy-Chowdhuri,Rashmi Kanagal Shamanna,Mark J. Routbort,L. Jeffrey Medeiros,Keyur P. Patel,Russell Broaddus,Aysegul A. Sahin,Rajyalakshmi Luthra +22 more
TL;DR: MIP microarray provided a robust assessment of genomic CNA of breast cancer and identified novel prognostic biomarkers in breast cancer-related gene alterations in DNA extracted from formalin-fixed paraffin-embedded tissue.