R
Ronald Hoffman
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 222
Citations - 7732
Ronald Hoffman is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Myelofibrosis & Stem cell. The author has an hindex of 37, co-authored 221 publications receiving 6460 citations.
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Hematology: Basic Principles and Practice
TL;DR: The author examines the immune system through the lens of Epstein-Barr Virus-Associated Diseases, as well as the biology of Stem Cells and Disorders of Hematopoiesis, and the approach to the Adult and Child with Anemia.
Journal ArticleDOI
Philadelphia chromosome-negative classical myeloproliferative neoplasms: Revised management recommendations from European LeukemiaNet
Tiziano Barbui,Ayalew Tefferi,Alessandro M. Vannucchi,Francesco Passamonti,Richard T. Silver,Ronald Hoffman,Srdan Verstovsek,Ruben A. Mesa,Jean-Jacques Kiladjian,Rèdiger Hehlmann,Andreas Reiter,Francisco Cervantes,Claire N. Harrison,Mary F. Mc Mullin,Hans Carl Hasselbalch,Steffen Koschmieder,Monia Marchetti,Andrea Bacigalupo,Guido Finazzi,Nicolaus Kroeger,Martin Griesshammer,Gunnar Birgegård,Giovanni Barosi +22 more
TL;DR: This document updates the recommendations on the management of Philadelphia chromosome-negative myeloproliferative neoplasms (Ph-neg MPNs), and both recombinant interferon alpha and the JAK1/JAK2 inhibitor ruxolitinib are recommended as second-line therapies for PV patients who are intolerant or have inadequate response to hydroxyurea.
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Revised response criteria for myelofibrosis: International Working Group-Myeloproliferative Neoplasms Research and Treatment (IWG-MRT) and European LeukemiaNet (ELN) consensus report
Ayalew Tefferi,Francisco Cervantes,Ruben A. Mesa,Francesco Passamonti,Srdan Verstovsek,Alessandro M. Vannucchi,Jason Gotlib,Brigitte Dupriez,Animesh Pardanani,Claire N. Harrison,Ronald Hoffman,Heinz Gisslinger,Nicolaus Kröger,Juergen Thiele,Tiziano Barbui,Giovanni Barosi +15 more
TL;DR: The current document is a revision of the International Working Group-Myeloproliferative Neoplasms Research and Treatment criteria for treatment response in myelofibrosis and represents a collaborative effort by the IWG-MRT and the European LeukemiaNet to objectively assess the value of new drugs in inducing morphologic remission or improvement in MF-associated symptomatic burden.
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Pacritinib vs Best Available Therapy, Including Ruxolitinib, in Patients With Myelofibrosis: A Randomized Clinical Trial
John Mascarenhas,Ronald Hoffman,Moshe Talpaz,Aaron T. Gerds,Brady L. Stein,Vikas Gupta,Anita Szoke,Mark Drummond,Alexander Pristupa,Tanya Granston,Robert Daly,Suliman Al-Fayoumi,Jennifer A. Callahan,Jack W. Singer,Jason Gotlib,Catriona Jamieson,Claire N. Harrison,Ruben A. Mesa,Srdan Verstovsek +18 more
TL;DR: In patients with myelofibrosis and thrombocytopenia, including those with prior anti-JAK therapy, pacritinib twice daily was more effective than BAT, including ruxolitinib, for reducing splenomegaly and symptoms.
Journal ArticleDOI
Revised response criteria for polycythemia vera and essential thrombocythemia: an ELN and IWG-MRT consensus project
Giovanni Barosi,Ruben A. Mesa,Guido Finazzi,Claire N. Harrison,Jean-Jacques Kiladjian,Eva Lengfelder,Mary Frances McMullin,Francesco Passamonti,Alessandro M. Vannucchi,Carlos Besses,Heinz Gisslinger,Jan Samuelsson,Srdan Verstovsek,Ronald Hoffman,Animesh Pardanani,Francisco Cervantes,Ayalew Tefferi,Tiziano Barbui +17 more
TL;DR: Revised recommendations for assessing response in ET and PV are presented by a working group established by ELN and International Working Group-Myeloproliferative Neoplasms Research and Treatment that include new definitions of complete and partial remission that include a standardized symptom assessment form.