R
Rosa S.P Beddington
Researcher at National Institute for Medical Research
Publications - 14
Citations - 8089
Rosa S.P Beddington is an academic researcher from National Institute for Medical Research. The author has contributed to research in topics: Gastrulation & Ectoderm. The author has an hindex of 13, co-authored 14 publications receiving 7858 citations. Previous affiliations of Rosa S.P Beddington include University of Oxford.
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Journal ArticleDOI
Cbfa1, a Candidate Gene for Cleidocranial Dysplasia Syndrome, Is Essential for Osteoblast Differentiation and Bone Development
Florian Otto,Anders P Thornell,Tessa Crompton,Angela Denzel,Kimberly C Gilmour,Ian R Rosewell,Gordon Stamp,Rosa S.P Beddington,Stefan Mundlos,Bjorn R. Olsen,Paul B. Selby,Michael John Owen +11 more
TL;DR: The Cbfa1 gene is essential for osteoblast differentiation and bone formation, and the C bfa1 heterozygous mouse is a paradigm for a human skeletal disorder.
Manipulating the Mouse Embryo
Brigid L.M. Hogan,Rosa S.P Beddington,Frank Costantini,Gen Me,Ming Li Wang,Julia Dewdney,David Bouchez,Stacie K. Loftus +7 more
TL;DR: This manual of proven distinction is again an authoritative and comprehensive source of technical guidance for experienced investigators and an essential resource for newcomers to mammalian genetics and embryology.
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Axis Development and Early Asymmetry in Mammals
TL;DR: This document apologizes to all those whose work has not been cited due to space constraints and thanks Peter Rigby and Tristan Rodriguez for their helpful discussion.
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An assessment of the developmental potential of embryonic stem cells in the midgestation mouse embryo.
TL;DR: Analysis of midgestation chimaeras, by electrophoretic separation of glucose phosphate isomerase (GPI) isozymes, showed that ES cells were capable of colonizing trophectoderm and primitive endoderm derivatives at a low frequency, as well as producing a high rate ofChimaerism in tissues of the fetus and extraembryonic mesoderm.
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Anterior primitive endoderm may be responsible for patterning the anterior neural plate in the mouse embryo
TL;DR: It is proposed that primitive endoderm is responsible for the initial induction of rostral identity in the embryo, and in particular for the correct definition of the future prosencephalic neurectoderm.