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Rukkumani Rajagopalan

Researcher at Pondicherry University

Publications -  38
Citations -  601

Rukkumani Rajagopalan is an academic researcher from Pondicherry University. The author has contributed to research in topics: Curcumin & Medicine. The author has an hindex of 13, co-authored 33 publications receiving 450 citations. Previous affiliations of Rukkumani Rajagopalan include University of Madras & Centre for Cellular and Molecular Biology.

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Journal ArticleDOI

Antiproliferative and Apoptotic Effects of Sesbania grandiflora Leaves in Human Cancer Cells

Sankar Pajaniradje, +4 more
- 15 May 2014 - 
TL;DR: The results prove that the medicinal plant S. grandiflora can be explored further for promising candidate molecules to combat cancer, especially lung cancer.
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Mechanism of apoptotic induction in human breast cancer cell, MCF-7, by an analog of curcumin in comparison with curcumin – An in vitro and in silico approach

Kumaravel Mohankumar, +8 more
- 05 Mar 2014 - 
TL;DR: Overall results showed that BDMC-A induced apoptosis more effectively compared to curcumin and the activity can be attributed to the presence of hydroxyl group in the ortho position in its structure.
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Recombinant fusion proteins TAT‐Mu, Mu and Mu‐Mu mediate efficient non‐viral gene delivery

Rukkumani Rajagopalan, +4 more
- 01 Apr 2007 - 
TL;DR: A recombinant approach to make fusion proteins with motifs for DNA‐binding ability, Mu and membrane transduction domains, TAT, and tested them for their DNA‐ binding, uptake and transfection efficiencies.
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Phytochemical screening and analysis of antioxidant properties of aqueous extract of wheatgrass.

Varalakshmi Durairaj, +4 more
- 01 Sep 2014 - 
TL;DR: In this article, the phytochemical constituents and antioxidant properties of wheatgrass extract were evaluated and concluded that wheatgrass aqueous extract contains various effective compounds such as squalene, caryophyllene and amyrins.
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BDMC-A, an analog of curcumin, inhibits markers of invasion, angiogenesis, and metastasis in breast cancer cells via NF-κB pathway--A comparative study with curcumin.

Kumaravel Mohankumar, +10 more
- 01 Aug 2015 - 
TL;DR: Investigation of the inhibitory effects of BDMC-A, an analog of curcumin, on invasion, angiogenesis and metastasis markers using in vitro with MCF-7 cells and in silico studies proved that BD MC-A has more potential thanCurcumin.