R
Rukkumani Rajagopalan
Researcher at Pondicherry University
Publications - 38
Citations - 601
Rukkumani Rajagopalan is an academic researcher from Pondicherry University. The author has contributed to research in topics: Curcumin & Medicine. The author has an hindex of 13, co-authored 33 publications receiving 450 citations. Previous affiliations of Rukkumani Rajagopalan include University of Madras & Centre for Cellular and Molecular Biology.
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Journal ArticleDOI
Antiproliferative and Apoptotic Effects of Sesbania grandiflora Leaves in Human Cancer Cells
Sankar Pajaniradje,Kumaravel Mohankumar,Ramya Pamidimukkala,Srividya Subramanian,Rukkumani Rajagopalan +4 more
TL;DR: The results prove that the medicinal plant S. grandiflora can be explored further for promising candidate molecules to combat cancer, especially lung cancer.
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Mechanism of apoptotic induction in human breast cancer cell, MCF-7, by an analog of curcumin in comparison with curcumin – An in vitro and in silico approach
Kumaravel Mohankumar,Sankar Pajaniradje,Subhashree Sridharan,Vivek Singh,Larance Ronsard,Akhil C. Banerjea,Chellakkan Selvanesan Benson,Mohane Selvaraj Coumar,Rukkumani Rajagopalan +8 more
TL;DR: Overall results showed that BDMC-A induced apoptosis more effectively compared to curcumin and the activity can be attributed to the presence of hydroxyl group in the ortho position in its structure.
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Recombinant fusion proteins TAT‐Mu, Mu and Mu‐Mu mediate efficient non‐viral gene delivery
TL;DR: A recombinant approach to make fusion proteins with motifs for DNA‐binding ability, Mu and membrane transduction domains, TAT, and tested them for their DNA‐ binding, uptake and transfection efficiencies.
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Phytochemical screening and analysis of antioxidant properties of aqueous extract of wheatgrass.
Varalakshmi Durairaj,Muddasarul Hoda,Garima Shakya,Sankar Pajaniradje Preedia Babu,Rukkumani Rajagopalan +4 more
TL;DR: In this article, the phytochemical constituents and antioxidant properties of wheatgrass extract were evaluated and concluded that wheatgrass aqueous extract contains various effective compounds such as squalene, caryophyllene and amyrins.
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BDMC-A, an analog of curcumin, inhibits markers of invasion, angiogenesis, and metastasis in breast cancer cells via NF-κB pathway--A comparative study with curcumin.
Kumaravel Mohankumar,Subhashree Sridharan,Sankar Pajaniradje,Vivek Singh,Larance Ronsard,Akhil C. Banerjea,Dinesh Babu Somasundaram,Mohane Selvaraj Coumar,Latha Periyasamy,Rukkumani Rajagopalan,Rukkumani Rajagopalan +10 more
TL;DR: Investigation of the inhibitory effects of BDMC-A, an analog of curcumin, on invasion, angiogenesis and metastasis markers using in vitro with MCF-7 cells and in silico studies proved that BD MC-A has more potential thanCurcumin.