R
Ruth Y. Eberhardt
Researcher at Wellcome Trust Sanger Institute
Publications - 48
Citations - 36234
Ruth Y. Eberhardt is an academic researcher from Wellcome Trust Sanger Institute. The author has contributed to research in topics: Exome sequencing & Protein family. The author has an hindex of 26, co-authored 46 publications receiving 33148 citations. Previous affiliations of Ruth Y. Eberhardt include University of Cambridge & Swiss Institute of Bioinformatics.
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Journal ArticleDOI
The Pfam protein families database
Marco Punta,Penny Coggill,Ruth Y. Eberhardt,Jaina Mistry,John Tate,Chris Boursnell,Ningze Pang,Kristoffer Forslund,Goran Ceric,Jody Clements,Andreas Heger,Liisa Holm,Erik L. L. Sonnhammer,Sean R. Eddy,Alex Bateman,Robert D. Finn +15 more
TL;DR: The definition and use of family-specific, manually curated gathering thresholds are explained and some of the features of domains of unknown function (also known as DUFs) are discussed, which constitute a rapidly growing class of families within Pfam.
Journal ArticleDOI
Pfam: the protein families database.
Robert D. Finn,Alex Bateman,Jody Clements,Penelope Coggill,Ruth Y. Eberhardt,Sean R. Eddy,Andreas Heger,Kirstie Hetherington,Liisa Holm,Jaina Mistry,Erik L. L. Sonnhammer,John Tate,Marco Punta +12 more
TL;DR: Pfam as discussed by the authors is a widely used database of protein families, containing 14 831 manually curated entries in the current version, version 27.0, and has been updated several times since 2012.
Journal ArticleDOI
The Pfam protein families database: towards a more sustainable future
Robert D. Finn,Penelope Coggill,Ruth Y. Eberhardt,Ruth Y. Eberhardt,Sean R. Eddy,Sean R. Eddy,Jaina Mistry,Alex L. Mitchell,Simon C. Potter,Marco Punta,Marco Punta,Matloob Qureshi,Amaia Sangrador-Vegas,Gustavo A. Salazar,John Tate,John Tate,Alex Bateman +16 more
TL;DR: Pfam is now primarily based on the UniProtKB reference proteomes, with the counts of matched sequences and species reported on the website restricted to this smaller set, and the facility to view the relationship between families within a clan has been improved by the introduction of a new tool.
Journal ArticleDOI
The EMBL Nucleotide Sequence Database
Tamara Kulikova,Philippe Aldebert,Nicola Althorpe,Wendy Baker,Kirsty Bates,Paul Browne,Alexandra van den Broek,Guy Cochrane,Karyn Duggan,Ruth Y. Eberhardt,Nadeem Faruque,Maria Garcia-Pastor,Nicola Harte,Carola Kanz,Rasko Leinonen,Quan Lin,Vincent Lombard,Rodrigo Lopez,Renato Mancuso,Michelle McHale,Francesco Nardone,Ville Silventoinen,Peter Stoehr,Guenter Stoesser,Mary Ann Tuli,Katerina Tzouvara,Robert Vaughan,Dan Wu,Weimin Zhu,Rolf Apweiler +29 more
TL;DR: Changes over the past year include the removal of the sequence length limit, the launch of the EMBLCDSs dataset, extension of the Sequence Version Archive functionality and the revision of quality rules for TPA data.
The Universal Protein Resource (UniProt) in 2010
Rolf Apweiler,Maria Jesus Martin,Claire O'Donovan,Michele Magrane,Yasmin Alam-Faruque,Ricardo Antunes,Daniel Barrell,Benoit Bely,M Bingley,David Binns,Lynette Bower,Paul Browne,WM Chan,E. Dimmer,Ruth Y. Eberhardt,A. Fedotov,Rebecca E. Foulger,John S. Garavelli,Rachael P. Huntley,Julius O.B. Jacobsen,M. Kleen,Kati Laiho,Rasko Leinonen,Duncan Legge,Quan Lin,W Liu,Jie Luo,Sandra Orchard,Samuel Patient,Diego Poggioli,Manuela Pruess,Matthew Corbett,G di Martino,M Donnelly,P van Rensburg,Amos Marc Bairoch,Lydie Bougueleret,Ioannis Xenarios,S Altairac,Andrea H. Auchincloss,Ghislaine Argoud-Puy,Kristian B. Axelsen,Delphine Baratin,M. C. Blatter,Brigitte Boeckmann,Jerven Bolleman,L. Bollondi,Emmanuel Boutet,SB Quintaje,Lionel Breuza,Alan Bridge,E. Decastro,L Ciapina,D Coral,Elisabeth Coudert,Isabelle Cusin,G Delbard,M Doche,Dolnide Dornevil,Paula Duek Roggli,Séverine Duvaud,Anne Estreicher,L Famiglietti,M Feuermann,Sebastien Gehant,N. Farriol-Mathis,Serenella Ferro,Elisabeth Gasteiger,Alain Gateau,Gerritsen,Arnaud Gos,Nadine Gruaz-Gumowski,Ursula Hinz,Chantal Hulo,Nicolas Hulo,J. James,S. Jimenez,Florence Jungo,T. Kappler,Guillaume Keller,Corinne Lachaize,L Lane-Guermonprez,Petra S. Langendijk-Genevaux,Lara,P Lemercier,Damien Lieberherr,Tdo Lima,Mangold,Xavier D. Martin,Patrick Masson,M. Moinat,Anne Morgat,Anaïs Mottaz,Salvo Paesano,Ivo Pedruzzi,Sandrine Pilbout,Pillet,Sylvain Poux,Monica Pozzato,Nicole Redaschi,Catherine Rivoire,Bernd Roechert,Maria Victoria Schneider,Christian J. A. Sigrist,K Sonesson,S Staehli,Eleanor J Stanley,Andre Stutz,Shyamala Sundaram,Michael Tognolli,Laure Verbregue,A-L Veuthey,L Yip,L Zuletta,Cathy H. Wu,Cecilia N. Arighi,Leslie Arminski,Winona C. Barker,Chuming Chen,Yingfei Chen,Z-Z Hu,Hongzhan Huang,Raja Mazumder,Peter B. McGarvey,Darren A. Natale,Jules Nchoutmboube,Natalia V. Petrova,N Subramanian,Baris E. Suzek,U. Ugochukwu,Sona Vasudevan,C. R. Vinayaka,LS Yeh,Jian Zhang +133 more