R
Ryo Horiguchi
Researcher at Graduate University for Advanced Studies
Publications - 14
Citations - 339
Ryo Horiguchi is an academic researcher from Graduate University for Advanced Studies. The author has contributed to research in topics: Protein subunit & Proteasome. The author has an hindex of 11, co-authored 14 publications receiving 320 citations. Previous affiliations of Ryo Horiguchi include Shizuoka University & National Institute for Basic Biology, Japan.
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Journal ArticleDOI
Initiation of Cyclin B Degradation by the 26S Proteasome upon Egg Activation
Toshinobu Tokumoto,Masakane Yamashita,Mika Tokumoto,Yoshinao Katsu,Ryo Horiguchi,Hiroko Kajiura,Yoshitaka Nagahama +6 more
TL;DR: The results of this study indicate that Mutant cyclin at K57 was resistant to both digestion by the 26S proteasome and degradation at metaphase/anaphase transition in Xenopus egg extracts, indicating that the destruction of cyclin B is initiated by the ATP-dependent and ubiquitin-independent proteolytic activity of 26S Proteasome through the first cutting in the NH2 terminus ofcyclin.
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Diethylstilbestrol induces fish oocyte maturation.
TL;DR: An endocrine-disrupting chemical, diethylstilbestrol (DES), a nonsteroidal estrogen, triggers oocyte maturation in fish and the structural requirement for the action of DES is discussed based on results obtained with DES analogs.
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Two proteins, a goldfish 20S proteasome subunit and the protein interacting with 26S proteasome, change in the meiotic cell cycle.
Mika Tokumoto,Ryo Horiguchi,Ryo Horiguchi,Yoshitaka Nagahama,Katsutoshi Ishikawa,Toshinobu Tokumoto +5 more
TL;DR: The results suggest that the 26S proteasome is changed reversibly during the meiotic cell cycle by modification of its subunits and interactions between regulators.
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Exposure to diethylstilbestrol during embryonic and larval stages of medaka fish (Oryzias latipes) leads to sex reversal in genetic males and reduced gonad weight in genetic females.
TL;DR: Exposure to a potent nonsteroidal estrogen, diethylstilbestrol, has long-lasting effects on the gonadal development in genetic males (sex reversal) and females (reduced gonad weight) of medaka.
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Identification of a protein kinase which phosphorylates a subunit of the 26S proteasome and changes in its activity during meiotic cell cycle in goldfish oocytes.
TL;DR: Two-dimensional PAGE analysis showed that part of the alpha4 subunit of the 26S proteasome was phosphorylated by CKIalpha in vitro, demonstrating the role of the phosphorylation in the meiotic cell cycle in fish oocytes.