R
Ryu-Ichiro Hata
Researcher at Tokyo Medical and Dental University
Publications - 41
Citations - 1760
Ryu-Ichiro Hata is an academic researcher from Tokyo Medical and Dental University. The author has contributed to research in topics: Type I collagen & Chondroitin sulfate. The author has an hindex of 20, co-authored 39 publications receiving 1719 citations.
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L-ascorbic acid 2-phosphate stimulates collagen accumulation, cell proliferation, and formation of a three-dimensional tissuelike substance by skin fibroblasts
Ryu-Ichiro Hata,Haruki Senoo +1 more
TL;DR: Results indicate that Asc 2‐P is useful in culture systems as a long‐acting vitamin C derivative and also that it promotes reorganization of a three‐dimensional tissuelike substance from skin fibroblasts in culture by stimulating collagen accumulation in the fibro Blasts.
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A rapid and micro method for separation of acidic glycosaminoglycans by two-dimensional electrophoresis.
Ryu-Ichiro Hata,Yutaka Nagai +1 more
TL;DR: Electrophoretic separation of seven acidic glycosaminoglycans was accomplished by two-dimensional electrophoresis on a cellulose acetate strip and high resolving power and sensitivity make it possible to identify AGG in tissues in as small amounts as biopsy specimens.
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Biosynthesis of interstitial types of collagen by albumin-producing rat liver parenchymal cell (hepatocyte) clones in culture
TL;DR: The idea that parenchymal cells play an essential role in the heaptic connective tissue metabolism under normal and pathological conditions is supported.
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A micro colorimetric determination of acidic glycosaminoglycans by two dimensional electrophoresis on a cellulose acetate strip.
Ryu-Ichiro Hata,Yutaka Nagai +1 more
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Regulation of collagen metabolism and cell growth by epidermal growth factor and ascorbate in cultured human skin fibroblasts
Ryu-Ichiro Hata,Hironobu Sunada,Katsuhiko Arai,Toshiaki Sato,Yoshifumi Ninomiya,Yutaka Nagai,Haruki Senoo +6 more
TL;DR: The results suggest that the two growth-promoting factors, epidermal growth factor and L-ascorbate, modulate metabolism of extracellular matrix components as well as cell growth in a quite different manner in human skin fibroblasts.