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Yoshifumi Ninomiya
Researcher at Okayama University
Publications - 219
Citations - 11052
Yoshifumi Ninomiya is an academic researcher from Okayama University. The author has contributed to research in topics: Type IV collagen & Basement membrane. The author has an hindex of 57, co-authored 219 publications receiving 10471 citations. Previous affiliations of Yoshifumi Ninomiya include Texas A&M University.
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Journal ArticleDOI
Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development
Ernst Pöschl,Ursula Schlötzer-Schrehardt,Bent Brachvogel,Kenji Saito,Yoshifumi Ninomiya,Ulrike Mayer +5 more
TL;DR: It is suggested that laminin is sufficient for basement membrane-like matrices during early development, but at later stages the specific composition of components including collagen IV defines integrity, stability and functionality.
Journal ArticleDOI
A fibrillar collagen gene, Col11a1, is essential for skeletal morphogenesis
Yi Li,D A Lacerda,Matthew L. Warman,David R. Beier,Hidekatsu Yoshioka,Yoshifumi Ninomiya,Julia Thom Oxford,Nicholas P. Morris,K Andrikopoulos,F Ramirez,B B Wardell,G D Lifferth,Cory Teuscher,Scott R. Woodward,B A Taylor,Robert E. Seegmiller,Bjorn R. Olsen +16 more
TL;DR: This paper showed that the normal differentiation and spatial organization of growth plate chondrocytes is critially dependent on the presence of type XI collagen in cartilage extracellular matrix.
Journal ArticleDOI
New functions for non-collagenous domains of human collagen type IV. Novel integrin ligands inhibiting angiogenesis and tumor growth in vivo.
Eric Petitclerc,Ariel Boutaud,Archie Prestayko,Jingsong Xu,Yoshikazu Sado,Yoshifumi Ninomiya,Michael P. Sarras,Billy G. Hudson,Peter C. Brooks +8 more
TL;DR: It is suggested that specific NC1 domains of collagen type IV may represent an important new class of angiogenesis inhibitors.
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Differential expression of two basement membrane collagen genes, COL4A6 and COL4A5, demonstrated by immunofluorescence staining using peptide-specific monoclonal antibodies.
Yoshifumi Ninomiya,Megumi Kagawa,Ken Ichi Iyama,Ichiro Naito,Yumiko Kishiro,Jerome M. Seyer,Manabu Sugimoto,Toshitaka Oohashi,Yoshikazu Sado +8 more
TL;DR: It is demonstrated that in human adult kidney the alpha 6(IV) chain was never detected in the glomerular basement membrane, whereas the basement membranes of the Bowman's capsules and distal tubules were positive.
Journal ArticleDOI
Distinct Target-Derived Signals Organize Formation, Maturation, and Maintenance of Motor Nerve Terminals
Michael A. Fox,Joshua R. Sanes,Dorin-Bogdan Borza,Veraragavan P. Eswarakumar,Reinhard Fässler,Billy G. Hudson,Simon W. M. John,Yoshifumi Ninomiya,Vadim Pedchenko,Samuel L. Pfaff,Michelle N. Rheault,Yoshikazu Sado,Yoav Segal,Michael J. Werle,Hisashi Umemori,Hisashi Umemori +15 more
TL;DR: It is shown that three sets of organizers act sequentially to pattern motor nerve terminals: FGFs, beta2 laminins, and collagen alpha(IV) chains.