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S.A. Larsson

Researcher at Karolinska Institutet

Publications -  17
Citations -  6794

S.A. Larsson is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Data acquisition & Human cytomegalovirus. The author has an hindex of 10, co-authored 17 publications receiving 6071 citations.

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Geant4 developments and applications

TL;DR: GeGeant4 as mentioned in this paper is a software toolkit for the simulation of the passage of particles through matter, it is used by a large number of experiments and projects in a variety of application domains, including high energy physics, astrophysics and space science, medical physics and radiation protection.
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Cytomegalovirus DNA can be detected in peripheral blood mononuclear cells from all seropositive and most seronegative healthy blood donors over time.

TL;DR: All seropositive donors harbored latently infected PBMNCs, as demonstrated by the testing of samples collected over time, and a substantial proportion of seronegative individuals are CMV carriers and might transfer infection.
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CD13 (human aminopeptidase N) mediates human cytomegalovirus infection.

TL;DR: Human CD13 appears to mediate HCMV infection by a process that increases binding, but its enzymatic domain is not necessary for infection.
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Definition of a subset of human peripheral blood mononuclear cells that are permissive to human cytomegalovirus infection.

TL;DR: The capacity of HCMV to in vitro infect human peripheral blood mononuclear cells from healthy donors is tested and it is found that certain PBMC are permissive to H CMV infection.
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Cytomegalovirus-induced CD13-specific autoimmunity--a possible cause of chronic graft-vs-host disease.

TL;DR: CMV-induced CD13-specific autoimmunity contribute to tissue damage in chronic graft-versus-host reactions, and in vivo binding of IgM antibodies in aCD13-like fashion was preferentially demonstrated in skin and oral mucosa biopsies from the CD 13-immune patients suffering from cGVHD.