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TL;DR: Whole-genome scanning by spectral karyotyping allowed instantaneous visualization of defined emission spectra for each human chromosome after fluorescence in situ hybridization, and all human chromosomes were simultaneously identified.

TL;DR: It is concluded that the gain of chromosome 3q that occurs in HPV16-infected, aneuploid cells represents a pivotal genetic aberration at the transition from severe dysplasia/CIS to invasive cervical carcinoma.

TL;DR: Spectral karyotyping (SKY) is applied to chemically induced plasmocytomas, mammary gland tumours from transgenic mice overexpressing the c-myc onco-gene and thymomas from mice deficient for the ataxia telangiectasia (Atm) gene to demonstrate the potential of SKY to identify complex chromosomal aberrations in mouse models of human carcinogenesis.

TL;DR: A specific combination of multiple chromosomal losses characterizes chromophobe renal cell carcinomas and may help to differentiate them unequivocally from other types of kidney cancer.

TL;DR: Comparative genomic hybridization was applied for a comprehensive screening of under- and overrepresentation of genetic material in 13 autoptic small cell lung cancer specimens, finding the most abundant genetic changes include DNA losses of chromosome arms 3p, 5q, 10q, 13q, and 17p and DNA gains of 3q, 5p, 8q and 17q.