S. Hossein Fatemi

TL;DR: It is found that respiratory infection of pregnant mice with the human influenza virus yields offspring that display highly abnormal behavioral responses as adults, as in schizophrenia and autism, and maternal injection of the synthetic double-stranded RNA polyinosinic-polycytidylic acid causes a PPI deficit in the offspring in the absence of virus.

TL;DR: The neurodevelopmental model is related to a number of findings about schizophrenia and alternate explanations of the origin of schizophrenia including the neurodegenerative model are examined.

TL;DR: The diversity of opinions regarding the involvement of this important site in the pathology of autism will be observed, and points of consensus include presence of abnormal cerebellar anatomy, abnormal neurotransmitter systems, oxidative stress, Cerebellar motor and cognitive deficits, and neuroinflammation in subjects with autism.

TL;DR: The observed reductions in glutamic acid decarboxylase 65 and 67 kDa levels may account for reported increases of glutamate in blood and platelets of autistic subjects.

TL;DR: It is demonstrated that GABAA receptors are reduced in three brain regions that have previously been implicated in the pathogenesis of autism, suggesting widespread GABAergic dysfunction in the brains of subjects with autism.