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Stephen R. Dager
Researcher at University of Washington
Publications - 191
Citations - 13136
Stephen R. Dager is an academic researcher from University of Washington. The author has contributed to research in topics: Autism & Autism spectrum disorder. The author has an hindex of 53, co-authored 168 publications receiving 11584 citations. Previous affiliations of Stephen R. Dager include McGill University & University of North Carolina at Chapel Hill.
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Journal ArticleDOI
Brain structural abnormalities in young children with autism spectrum disorder.
B. F. Sparks,Seth D. Friedman,Dennis W. W. Shaw,Elizabeth Aylward,Denise R. Echelard,Alan A. Artru,Kenneth R. Maravilla,Jay N. Giedd,Jeffrey Munson,Geraldine Dawson,Stephen R. Dager +10 more
TL;DR: Structural findings suggest abnormal brain developmental processes early in the clinical course of autism, and research currently is underway to better elucidate mechanisms underlying mechanisms underlying these structural abnormalities and their longitudinal progression.
Journal ArticleDOI
Early brain development in infants at high risk for autism spectrum disorder
Heather C. Hazlett,Hongbin Gu,Brent C. Munsell,Sun Hyung Kim,Martin Styner,Jason J. Wolff,Jed T. Elison,Meghan R. Swanson,Hongtu Zhu,Kelly N. Botteron,D. Louis Collins,John N. Constantino,Stephen R. Dager,Annette Estes,Alan C. Evans,Vladimir S. Fonov,Guido Gerig,Penelope Kostopoulos,Robert C. McKinstry,Juhi Pandey,Sarah Paterson,John R. Pruett,Robert T. Schultz,Dennis W. W. Shaw,Lonnie Zwaigenbaum,Joseph Piven +25 more
TL;DR: It is shown that hyperexpansion of the cortical surface area between 6 and 12 months of age precedes brain volume overgrowth observed between 12 and 24 months in 15 high-risk infants who were diagnosed with autism at 24 months.
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Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder
Ryan K. C. Yuen,Daniele Merico,Matt Bookman,Jennifer L. Howe,Bhooma Thiruvahindrapuram,Rohan V. Patel,Joe Whitney,Nicole A. Deflaux,Jonathan Bingham,Zhuozhi Wang,Giovanna Pellecchia,Janet A. Buchanan,Susan Walker,Christian R. Marshall,Mohammed Uddin,Mehdi Zarrei,Eric Deneault,Lia D’Abate,Lia D’Abate,Ada J.S. Chan,Ada J.S. Chan,Stephanie Koyanagi,Tara Paton,Sergio L. Pereira,Ny Hoang,Worrawat Engchuan,Edward J Higginbotham,Karen Ho,Sylvia Lamoureux,Weili Li,Jeffrey R. MacDonald,Thomas Nalpathamkalam,Wilson W L Sung,Fiona Tsoi,John Wei,Lizhen Xu,Anne Marie Tassé,Emily Kirby,William Van Etten,Simon N. Twigger,Wendy Roberts,Irene Drmic,Sanne Jilderda,Bonnie Mackinnon Modi,Barbara Kellam,Michael J. Szego,Michael J. Szego,Cheryl Cytrynbaum,Rosanna Weksberg,Lonnie Zwaigenbaum,Marc Woodbury-Smith,Marc Woodbury-Smith,Jessica Brian,Lili Senman,Alana Iaboni,Krissy A.R. Doyle-Thomas,Ann Thompson,Christina Chrysler,Jonathan Leef,Tal Savion-Lemieux,Isabel M. Smith,Xudong Liu,Rob Nicolson,Vicki Seifer,Angie Fedele,Edwin H. Cook,Stephen R. Dager,Annette Estes,Louise Gallagher,Beth A. Malow,Jeremy R. Parr,Sarah J. Spence,Jacob A. S. Vorstman,Brendan J. Frey,James T. Robinson,Lisa J. Strug,Lisa J. Strug,Bridget A. Fernandez,Mayada Elsabbagh,Melissa T. Carter,Joachim Hallmayer,Bartha Maria Knoppers,Evdokia Anagnostou,Peter Szatmari,Peter Szatmari,Robert H. Ring,David Glazer,Mathew T. Pletcher,Stephen W. Scherer,Stephen W. Scherer +89 more
TL;DR: Se sequencing of 5,205 samples from families with ASD, accompanied by clinical information, creating a database accessible on a cloud platform and through a controlled-access internet portal that identified 18 new candidate ASD-risk genes and found that participants bearing mutations in susceptibility genes had significantly lower adaptive ability.
Journal ArticleDOI
Consensus Paper: Pathological Role of the Cerebellum in Autism
S. Hossein Fatemi,Kimberly A. Aldinger,Paul Ashwood,Margaret L. Bauman,Charles D. Blaha,Gene J. Blatt,Abha Chauhan,Ved Chauhan,Stephen R. Dager,Price E. Dickson,Annette Estes,Dan Goldowitz,Detlef H. Heck,Thomas L. Kemper,Bryan H. King,Loren A. Martin,Kathleen J. Millen,Guy Mittleman,Matthew W. Mosconi,Antonio M. Persico,John A. Sweeney,Sara Jane Webb,John P. Welsh +22 more
TL;DR: The diversity of opinions regarding the involvement of this important site in the pathology of autism will be observed, and points of consensus include presence of abnormal cerebellar anatomy, abnormal neurotransmitter systems, oxidative stress, Cerebellar motor and cognitive deficits, and neuroinflammation in subjects with autism.
Journal ArticleDOI
Differences in white matter fiber tract development present from 6 to 24 months in infants with autism.
Jason J. Wolff,Hongbin Gu,Guido Gerig,Jed T. Elison,Martin Styner,Sylvain Gouttard,Kelly N. Botteron,Stephen R. Dager,Geraldine Dawson,Annette Estes,Alan C. Evans,Heather C. Hazlett,Penelope Kostopoulos,Robert C. McKinstry,Sarah Paterson,Robert T. Schultz,Lonnie Zwaigenbaum,Joseph Piven +17 more
TL;DR: It is suggested that aberrant development of white matter pathways may precede the manifestation of autistic symptoms in the first year of life in high-risk infants who developed autism spectrum disorders by 24 months.