S
S. Joseph Leibovich
Researcher at Rutgers University
Publications - 11
Citations - 2792
S. Joseph Leibovich is an academic researcher from Rutgers University. The author has contributed to research in topics: Adenosine & Adenosine A3 receptor. The author has an hindex of 10, co-authored 11 publications receiving 2528 citations. Previous affiliations of S. Joseph Leibovich include University of Medicine and Dentistry of New Jersey.
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Journal ArticleDOI
Inflammatory cells during wound repair: the good, the bad and the ugly
Paul Martin,S. Joseph Leibovich +1 more
TL;DR: New views on how regulation of the migration of inflammatory cells to sites of tissue damage might guide therapeutic strategies for modulating the inflammatory response are discussed.
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Adenosine promotes alternative macrophage activation via A2A and A2B receptors
Balázs Csóka,Zsolt Selmeczy,Balázs Koscsó,Zoltán Németh,Zoltán Németh,Pal Pacher,Peter J. Murray,Diane Kepka-Lenhart,Sidney M. Morris,William C. Gause,S. Joseph Leibovich,György Haskó,György Haskó +12 more
TL;DR: It is proposed that adenosine receptor activation suppresses inflammation and promotes tissue restitution, in part, by promoting alternative macrophage activation.
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An Angiogenic Switch in Macrophages Involving Synergy between Toll-Like Receptors 2, 4, 7, and 9 and Adenosine A2A Receptors
Grace Pinhal-Enfield,Madhuri Ramanathan,György Haskó,Stefanie N. Vogel,Andrew L. Salzman,Geert-Jan Boons,S. Joseph Leibovich +6 more
TL;DR: It is demonstrated that TLR2, TLR7, and TLR9, but not TLR3 andTLR5 agonists, also synergize with A(2A)R agonists and adenosine to up-regulate VEGF, while simultaneously strongly down-regulating TNFalpha expression.
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Adenosine Augments IL-10 Production by Macrophages through an A2B Receptor-Mediated Posttranscriptional Mechanism
Zoltán Németh,Carol S. Lutz,Balázs Csóka,Edwin A. Deitch,S. Joseph Leibovich,William C. Gause,Masahide Tone,Pal Pacher,E. Sylvester Vizi,György Haskó +9 more
TL;DR: It is demonstrated that adenosine receptor occupancy increasesIL-10 production by LPS-stimulated macrophages without affecting IL-10 promoter activity and IL- 10 mRNA levels, indicating a posttranscriptional mechanism.
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Effects of nitric oxide releasing poly(vinyl alcohol) hydrogel dressings on dermal wound healing in diabetic mice
TL;DR: The results of this study suggest that exogenous NO released from a hydrogel wound dressing has potential to modulate wound healing.