S
S M Oberhaus
Researcher at Anschutz Medical Campus
Publications - 15
Citations - 1330
S M Oberhaus is an academic researcher from Anschutz Medical Campus. The author has contributed to research in topics: Apoptosis & DNA polymerase. The author has an hindex of 12, co-authored 15 publications receiving 1304 citations. Previous affiliations of S M Oberhaus include Vanderbilt University & East Carolina University.
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Journal ArticleDOI
Expression of a gene encoding a scorpion insectotoxin peptide in yeast, bacteria and plants.
Sheng-Zhi Pang,S M Oberhaus,Jeanette L. Rasmussen,Douglas C. Knipple,Jeffrey R. Bloomquist,Donald H. Dean,Kim D. Bowman,John C. Sanford +7 more
TL;DR: The yeast and bacterial expression systems described here may be useful for further studies on the problem of expressing a biologically active peptide before scorpion toxins might be used for the genetic engineering of plants for insect resistance.
Journal ArticleDOI
Differences in the capacity of reovirus strains to induce apoptosis are determined by the viral attachment protein sigma 1.
Kenneth L. Tyler,Margaret K.T. Squier,Steven E. Rodgers,Benjamin E. Schneider,S M Oberhaus,Theresa A. Grdina,J. John Cohen,Terence S. Dermody +7 more
TL;DR: It is shown that murine L929 cells infected with prototype reovirus strains type 1 Lang and type 3 Dearing undergo apoptosis and that T3D induces apoptosis to a substantially greater extent than T1L, and it is suggested that interaction of virions with cell surface receptors is an essential step in this mechanism of cell killing.
Journal ArticleDOI
Detection of reovirus RNA in hepatobiliary tissues from patients with extrahepatic biliary atresia and choledochal cysts
Kenneth L. Tyler,Ronald J. Sokol,Ronald J. Sokol,S M Oberhaus,Mysan Le,Frederick M. Karrer,Frederick M. Karrer,Michael R. Narkewicz,Michael R. Narkewicz,R. Weslie Tyson,James Murphy,Robert L. Low,William R. Brown,William R. Brown +13 more
TL;DR: To determine whether reovirus infection is associated with these disorders, a sensitive and specific reverse‐transcriptase polymerase chain reaction (RT‐PCR) technique was used designed to amplify a portion of the reov virus L1 gene segment from extracts of liver and/or biliary tissues.
Journal ArticleDOI
Signal transduction, cell cycle regulatory, and anti-apoptotic pathways regulated by IL-3 in hematopoietic cells : possible sites for intervention with anti-neoplastic drugs
William L. Blalock,Caroline Weinstein-Oppenheimer,Caroline Weinstein-Oppenheimer,Fumin Chang,P. E. Hoyle,X. Y. Wang,P. A. Algate,Richard A. Franklin,S M Oberhaus,Linda S. Steelman,James A. McCubrey +10 more
TL;DR: This review focuses on the current understanding of how hematopoietic cytokines such as IL-3, as well as its cognate receptor, are expressed and the mechanisms by which they transmit their growth regulatory signals.
Journal ArticleDOI
Reovirus infection and tissue injury in the mouse central nervous system are associated with apoptosis.
TL;DR: It is reported that T3D induces apoptosis in infected mouse brain tissue, suggesting that virus-induced apoptosis is a mechanism of cell death, tissue injury, and mortality in reovirus-infected mice.