S
Sachiko Tsukamoto
Researcher at Kumamoto University
Publications - 196
Citations - 4854
Sachiko Tsukamoto is an academic researcher from Kumamoto University. The author has contributed to research in topics: Indole test & Proteasome inhibitor. The author has an hindex of 39, co-authored 187 publications receiving 4232 citations. Previous affiliations of Sachiko Tsukamoto include University of Amsterdam & Sam Ratulangi University.
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Journal ArticleDOI
Notoamides A–D: Prenylated Indole Alkaloids Isolated from a Marine‐Derived Fungus, Aspergillus sp.
Hikaru Kato,Takushi Yoshida,Takanori Tokue,Yuka Nojiri,Hiroshi Hirota,Tomihisa Ohta,Robert M. Williams,Robert M. Williams,Sachiko Tsukamoto +8 more
TL;DR: Six new prenylated indole alkaloids, named notoamides F−K (8−13), were isolated from a marine-derived Aspergillus sp.
Journal ArticleDOI
Asymmetric total syntheses of (+)- and (−)-versicolamide B and biosynthetic implications
TL;DR: Experimental validation of the proposed biosynthetic Diels-Alder construction, coupled with the secondary metabolite profile of the producing fungi, reveals that each Aspergillus species has evolved enantiomerically distinct indole oxidases, as well as enantiomersically distinct Diels -Alderases.
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Ceratinamides A and B: New Antifouling Dibromotyrosine Derivatives from the Marine Sponge Pseudoceratina purpurea
TL;DR: Ceratinamides A and B (1 and 2 ), new bromotyrosine derivatives, have been isolated from the marine sponge Pseudoceratina purpurea, along with the known psammaplysins A ( 3 ) and E ( 4 ), ceratinamine ( 5 ), moloka'iamine ( 6 ), pseudoceratinidine ( 7 ), and 4,5-dibromopyrrole-2-carbamide (8 ). Their structures were elucidated on the basis of spectral data as discussed by the authors.
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Genome-based characterization of two prenylation steps in the assembly of the stephacidin and notoamide anticancer agents in a marine-derived aspergillus sp.
Yousong Ding,Jeffrey R. de Wet,James D. Cavalcoli,Shengying Li,Thomas J. Greshock,Thomas J. Greshock,Kenneth A. Miller,Kenneth A. Miller,Jennifer M. Finefield,Jennifer M. Finefield,James D. Sunderhaus,James D. Sunderhaus,Timothy J. McAfoos,Timothy J. McAfoos,Sachiko Tsukamoto,Robert M. Williams,Robert M. Williams,David H. Sherman +17 more
TL;DR: The results establish the early steps for creation of the prenylated indole alkaloid structure and suggest a scheme for the biosynthesis of stephacidin and notoamide metabolites, providing the first genetic and biochemical insights for understanding the structural diversity of this important family of fungal alkaloids.
Journal ArticleDOI
Notoamides F-K, prenylated indole alkaloids isolated from a marine-derived Aspergillus sp.
Sachiko Tsukamoto,Hikaru Kato,Masayuki Samizo,Yuka Nojiri,Hiroyuki Onuki,Hiroshi Hirota,Tomihisa Ohta +6 more
TL;DR: Six new prenylated indole alkaloids, named notoamides F-K (8-13), were isolated from a marine-derived Aspergillus sp.