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Sajid Nadeem

Researcher at Council of Scientific and Industrial Research

Publications -  13
Citations -  383

Sajid Nadeem is an academic researcher from Council of Scientific and Industrial Research. The author has contributed to research in topics: Mycobacterium tuberculosis & BCG vaccine. The author has an hindex of 7, co-authored 13 publications receiving 250 citations. Previous affiliations of Sajid Nadeem include University of Alabama at Birmingham & Techno India.

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Potential Role of Gut Microbiota in Induction and Regulation of Innate Immune Memory.

TL;DR: How gut microbiota can influence the generation of innate memory and functional reprogramming of bone marrow progenitors that helps in protection against infections is discussed.
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Alteration in the gut microbiota provokes susceptibility to tuberculosis

TL;DR: The novel role of gut microbes in the susceptibility to TB and its prevention by microbial implants is demonstrated for the first time and in future, microbial therapies may help in treating patients suffering from TB.
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Signaling through NOD-2 and TLR-4 Bolsters the T cell Priming Capability of Dendritic cells by Inducing Autophagy

TL;DR: This study signifies that NOD-2 and TLR-4 exhibit synergism in invigorating the activity of DCs and this strategy may have significant immunotherapeutic potential in bolstering the function ofDCs and thus improving the immunity against pathogens.
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The Role of Host-Generated H2S in Microbial Pathogenesis: New Perspectives on Tuberculosis.

TL;DR: The current understanding of the role of host-derived H2S in tuberculosis (TB) disease, including its influences on host immunity and bioenergetics, and on Mycobacterium tuberculosis (Mtb) growth and survival is described.
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A novel therapeutic strategy of lipidated promiscuous peptide against Mycobacterium tuberculosis by eliciting Th1 and Th17 immunity of host.

TL;DR: D-L91 therapy can invigorate drugs potency to treat tuberculosis patients and reduce the dose and duration of drug-regime and the immune response observed in animals could be replicated using T cells of tuberculosis patients on drug therapy.