Sang Mo Kwon

TL;DR: The clinical implications of angiogenesis are reviewed and pro- and antiangiogenic agents that offer potential therapy for cancer and other angiogenic diseases are discussed.

TL;DR: It is suggested that TNF-α CM stimulates angiogenesis and tissue repair through an increase in homing of EPCs through paracrine mechanisms involving IL-6 and IL-8.

TL;DR: Investigation of the effects of WKYMVm, a selective FPR2 agonist isolated by screening synthetic peptide libraries, on homing ability of ECFCs and vascular regeneration of ischemic tissues suggests that WKYVm promotes repair of isChemic tissues by stimulating homing of EC FCs and neovascularization via a F PR2‐dependent mechanism.

TL;DR: Ex vivo expansion protocols involving hypoxic preconditioning that are suitable for efficiently expanding old EPCs without senescence through modulation of the hypoxia-induced hypoxIA-inducible factor-1&agr;–TWIST-p21 axis are introduced.

TL;DR: The vasculogenic potential of endothelial progenitor cells at various stages of differentiation is impaired in diabetes and thus may account for impaired ischemia-induced vasculogenesis observed clinically.