Sanjiv Neupane

TL;DR: The high prevalence of multidrug resistance in bacterial uropathogens was observed, and resistance patterns were alarmingly higher for amoxycillin, co-trimoxazole, flouroquinolones and third-generation cephalosporins, which necessitate the re-evaluation of first and second line therapies for UTI.

TL;DR: Ethanolic extracts of 16 different traditionally used medicinal plants of Nepal against 13 clinical and 2 reference bacterial species using microbroth dilution method were found to exert a range of in vitro growth inhibitory action against the tested bacterial species.

TL;DR: Mouse B3glct mutants developed craniofacial and skeletal abnormalities comparable to PTRPLS and tested the role of B3GLCT in enabling function of ADAMTS9 and ADAMts20, two highly conserved targets whose functions are well-characterized in mouse development, suggesting that the developmental defects in P TRPLS result from disruption of a subset of highly sensitive POFUT2/B3 GLCT targets such as ADAM TS20.

TL;DR: It is proposed that developmental stage-specific Grhl3 plays a significant role in CVP morphogenesis not by just disruption of epithelial integrity but by regulating epithelial cell proliferation, apoptosis, and migration via Shh, Wnt, and apoptosis signaling during mouse embryogenesis.

TL;DR: Cyclosporine A eyedrops with SNEDDS have improved physicochemical properties and treatment efficacy in BAC-induced dry eye disease, in contrast to the high turbidity and unstable pH of C-CsA.