S
Sarah E. Ackerman
Researcher at Rockefeller University
Publications - 5
Citations - 445
Sarah E. Ackerman is an academic researcher from Rockefeller University. The author has contributed to research in topics: Adipose tissue & PRDM16. The author has an hindex of 4, co-authored 5 publications receiving 285 citations.
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Journal ArticleDOI
Three-Dimensional Adipose Tissue Imaging Reveals Regional Variation in Beige Fat Biogenesis and PRDM16-Dependent Sympathetic Neurite Density.
Jingyi Chi,Zhuhao Wu,Chan Hee J. Choi,Chan Hee J. Choi,Lily Nguyen,Saba Tegegne,Sarah E. Ackerman,Audrey Crane,François Marchildon,Marc Tessier-Lavigne,Marc Tessier-Lavigne,Paul Cohen +11 more
TL;DR: A whole-tissue clearing method for adipose is introduced that permits immunolabeling and three-dimensional profiling of structures including thermogenic adipocytes and sympathetic innervation and reveals a previously undescribed mode of regulation of the sympathetic nervous system by adipocytes.
Journal ArticleDOI
Sequencing and cloning of antigen-specific antibodies from mouse memory B cells
Lotta von Boehmer,Cassie Liu,Sarah E. Ackerman,Alexander D. Gitlin,Qiao Wang,Anna Gazumyan,Anna Gazumyan,Michel C. Nussenzweig,Michel C. Nussenzweig +8 more
TL;DR: A protocol to sequence and clone the variable antibody region of single antigen-specific mouse memory B cells for antibody production and improves the amplification efficiency of antibody variable genes and accelerates the cloning workflow is described.
Journal ArticleDOI
Insights into the Link Between Obesity and Cancer
TL;DR: The cellular and molecular pathways that appear to be involved in obesity-driven cancer are reviewed and possible therapeutic considerations are described and important unanswered questions in the field are highlighted.
Journal ArticleDOI
Creatine-mediated crosstalk between adipocytes and cancer cells regulates obesity-driven breast cancer.
Olivia A. Maguire,Olivia A. Maguire,Sarah E. Ackerman,Sarah K. Szwed,Sarah K. Szwed,Aarthi V. Maganti,François Marchildon,Xiaojing Huang,Xiaojing Huang,Daniel J. Kramer,Daniel J. Kramer,Adriana Rosas-Villegas,Rebecca G. Gelfer,Lauren E. Turner,Victor Ceballos,Asal Hejazi,Bozena Samborska,Janane F. Rahbani,Christien B. Dykstra,Matthew G. Annis,Ji Dung Luo,Thomas L. Carroll,Caroline S. Jiang,Andrew J. Dannenberg,Peter M. Siegel,Sarah A. Tersey,Raghavendra G. Mirmira,Lawrence Kazak,Paul Cohen +28 more
TL;DR: In this paper, the role of crosstalk between mammary adipocytes and neoplastic cells in the tumor microenvironment (TME) was investigated for obesity-accelerated breast cancer.