Sarah J. Tarr

TL;DR: Estimates of multiplication rates of long-term laboratory adapted parasite clones and new clinical isolates remained stable over time for several isolates tested repeatedly up to three months after culture initiation, indicating considerable persistence of this important trait variation.

TL;DR: A genome-wide scan showed the most exceptional geographical divergence to be at the early gametocyte gene locus gdv1 which is essential for parasite sexual development and transmission, and a major structural dimorphism with alternative 1.5 kb and 1.0 kb sequence deletions was identified.

TL;DR: Analysis of multiple biological sample replicates greatly improves identification of genes variably expressed between different cultured parasite lines.

TL;DR: A highly biologically replicated whole transcriptome sequencing approach is used to identify the molecular signatures of variation associated with the phenotype switch in switched parasites, indicating changes in expression of a repertoire of genes not previously associated with erythrocyte invasion phenotypes.

TL;DR: In this article, a stand-alone malaria parasite propeptide-like protein, called SUB1-ProM, encoded by a conserved gene that lies in a highly syntenic locus adjacent to three of the four subtilisin-like genes in the Plasmodium genome.