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Sarah L. Fordyce

Researcher at University of Copenhagen

Publications -  20
Citations -  785

Sarah L. Fordyce is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Deep sequencing & Koala retrovirus. The author has an hindex of 12, co-authored 20 publications receiving 712 citations. Previous affiliations of Sarah L. Fordyce include American Museum of Natural History & Statens Serum Institut.

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Application and comparison of large-scale solution-based DNA capture-enrichment methods on ancient DNA

TL;DR: The performance of Agilent's SureSelect and Mycroarray's MySelect in-solution capture systems on Illumina sequencing libraries built from ancient maize to identify key factors influencing aDNA capture experiments and provide useful recommendations for those planning targeted-sequencing on aDNA.
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Second-generation Sequencing of Forensic STRs Using the Ion Torrent™ HID STR 10-plex and the Ion PGM™

TL;DR: Interestingly, full profiles were obtained for all biological samples from real crime and identification cases, in which only partial profiles were obtaining with PCR-CE assays, and the Ion Torrent™ HID STR 10-plex panel offers an all-in-one solution from amplification of STRs and amelogenin, and sequencing to data analysis.
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High-throughput sequencing of core STR loci for forensic genetic investigations using the Roche Genome Sequencer FLX platform

TL;DR: This paper presents an STR profiling method based on the use of the Roche Genome Sequencer (GS) FLX to simultaneously sequence multiple core STR loci and found DNA base substitutions and repeat sequence variations that would not have been identified using conventional STR typing.
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Evaluation of the Ion Torrent™ HID SNP 169-plex: A SNP typing assay developed for human identification by second generation sequencing.

TL;DR: The Ion PGM™ is a very promising platform for forensic genetics, however, the secondary sequence analysis software made wrong genotype calls from correctly sequenced alleles and these types of errors must be corrected before the platform can be used in case work.