S
Saraswati Sukumar
Researcher at Johns Hopkins University School of Medicine
Publications - 262
Citations - 28255
Saraswati Sukumar is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 77, co-authored 248 publications receiving 26027 citations. Previous affiliations of Saraswati Sukumar include Tufts University & Salk Institute for Biological Studies.
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Journal Article
Post-translation regulation inhibits Claudin-7 expression in invasive breast cancer cells.
TL;DR: Preliminary data strongly suggest that a specific regulatory mechanism appear to be occurring at post-translational level in invasive and metastatic breast cancer cells to tightly control the expression of a specific Claudin protein.
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A prospective study of adjuvant anastrozole and gene promoter methylation in the contralateral breast of high-risk women
Tatiana M. Prowell,Mary Jo Fackler,Pedram Argani,Nagi F. Khouri,Amanda L. Blackford,Karineh Shahverdi,Antonio C. Wolff,Nancy E. Davidson,Saraswati Sukumar,Vered Stearns +9 more
TL;DR: Postmenopausal women with hormone receptor-positive stage 0-III breast cancer who had completed local therapy, had an intact CLB, and would receive an AI as their sole adjuvant therapy were surveyed for the effect of anastrozole on breast density and circulating estrogens, and CLB gene methylation.
Proceedings ArticleDOI
Abstract P3-04-08: Expression of hormone-responsive genes in benign breast tissue varies with menstrual cycle phase and menopausal status
Hong Hu,Jun Wang,Oukseub Lee,Ali Shidfar,Sivaraman Iyer,David Ivancic,Robert T. Chatterton,Vered Stearns,Saraswati Sukumar,Seema A. Khan +9 more
TL;DR: These hormone-responsive genes are candidate MCP classifiers which could be applied to archived breast samples to assess whether biomarkers of breast cancer risk are stable across the menstrual cycle, since MCP and MPS variation is likely an important source of biological noise in studies of archived breast biopsy material.
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ETS genes in breast cancer: A step in the right direction
Xinyan Wu,Saraswati Sukumar +1 more
TL;DR: Commentary to: Profile of Ets Gene Expression in Human Breast Carcinoma Jin He, Yong Pan, Jianhua Hu, Constance Albarracin, Yun Wu and Jia Le Dai
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Capturing ctDNA from Unaltered Stationary and Flowing Plasma with dCas9.
TL;DR: The goal was to develop the first technology that can capture ctDNA from flowing unaltered plasma and show that the capture rate using turbulent flow was greater than that in laminar flow and stationary plasma.