S
Saskia B. J. Koch
Researcher at Radboud University Nijmegen
Publications - 64
Citations - 2251
Saskia B. J. Koch is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Medicine & Ventromedial prefrontal cortex. The author has an hindex of 20, co-authored 56 publications receiving 1605 citations. Previous affiliations of Saskia B. J. Koch include VU University Medical Center & Academic Medical Center.
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Journal ArticleDOI
Smaller Hippocampal Volume in Posttraumatic Stress Disorder: A Multisite ENIGMA-PGC Study: Subcortical Volumetry Results From Posttraumatic Stress Disorder Consortia
Mark W. Logue,Sanne J.H. van Rooij,Emily L. Dennis,Sarah L. Davis,Jasmeet P. Hayes,Jennifer S. Stevens,Maria Densmore,Courtney C. Haswell,Jonathan C Ipser,Saskia B. J. Koch,Mayuresh S. Korgaonkar,Lauren A.M. Lebois,Matthew Peverill,Justin T. Baker,Premika S.W. Boedhoe,Jessie L. Frijling,Staci A. Gruber,Ilan Harpaz-Rotem,Neda Jahanshad,Sheri Koopowitz,Ifat Levy,Laura Nawijn,Lauren K. O’Connor,Lauren K. O’Connor,Miranda Olff,David H. Salat,Margaret A. Sheridan,Jeffrey M. Spielberg,Mirjam van Zuiden,Sherry Winternitz,Jonathan D. Wolff,Erika J. Wolf,Xin Wang,Kristen M. Wrocklage,Chadi G. Abdallah,Richard A. Bryant,Elbert Geuze,Tanja Jovanovic,Milissa L. Kaufman,Anthony P. King,John H. Krystal,Jim Lagopoulos,Max R. Bennett,Ruth A. Lanius,Israel Liberzon,Regina E. McGlinchey,Katie A. McLaughlin,William P. Milberg,Mark W. Miller,Kerry J. Ressler,Kerry J. Ressler,Dick J. Veltman,Dan J. Stein,Kathleen Thomaes,Paul M. Thompson,Rajendra A. Morey +55 more
TL;DR: This large-scale neuroimaging consortium study on PTSD conducted by the Psychiatric Genomics Consortium-Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA) PTSD Working Group represents an important milestone in an ongoing collaborative effort to examine the neurobiological underpinnings of PTSD and the brain's response to trauma.
Journal ArticleDOI
Aberrant resting-state brain activity in posttraumatic stress disorder: a meta-analysis and systematic review
Saskia B. J. Koch,Mirjam van Zuiden,Laura Nawijn,Jessie L. Frijling,Dick J. Veltman,Miranda Olff +5 more
TL;DR: About 10% of trauma‐exposed individuals develop PTSD and a growing number of studies have investigated resting‐state abnormalities in PTSD, but inconsistent results suggest a need for a meta‐analysis and systematic review.
Journal ArticleDOI
Reward functioning in PTSD: A systematic review exploring the mechanisms underlying anhedonia
Laura Nawijn,Mirjam van Zuiden,Jessie L. Frijling,Saskia B. J. Koch,Dick J. Veltman,Miranda Olff +5 more
TL;DR: A systematic review of studies in which reward functioning was compared between PTSD patients and healthy control participants, or investigated in relation to PTSD symptom severity found decreased reward anticipation and approach and reduced hedonic responses were repeatedly observed in PTSD patients compared to healthy controls.
Journal ArticleDOI
Anterior prefrontal cortex inhibition impairs control over social emotional actions
Inge Volman,Inge Volman,Karin Roelofs,Karin Roelofs,Saskia B. J. Koch,Lennart Verhagen,Ivan Toni +6 more
TL;DR: These findings illustrate how exerting emotional control during social interactions requires the aPFC to coordinate rapid action selection processes, the detection of emotional conflicts, and the inhibition of emotionally-driven responses.
Journal ArticleDOI
Intranasal Oxytocin Normalizes Amygdala Functional Connectivity in Posttraumatic Stress Disorder
Saskia B. J. Koch,Mirjam van Zuiden,Laura Nawijn,Jessie L. Frijling,Dick J. Veltman,Miranda Olff +5 more
TL;DR: It is tentatively suggested that OT has the potential to diminish anxiety and fear expression of the amygdala in PTSD, either via increased control of the vmPFC over the CeM (males) or via decreased salience processing of the dACC and BLA (females).