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Jonathan C Ipser

Researcher at University of Cape Town

Publications -  103
Citations -  3730

Jonathan C Ipser is an academic researcher from University of Cape Town. The author has contributed to research in topics: Anxiety & Medicine. The author has an hindex of 29, co-authored 85 publications receiving 2970 citations. Previous affiliations of Jonathan C Ipser include Stellenbosch University.

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Pharmacotherapy for post traumatic stress disorder (PTSD)

TL;DR: The findings of this review support the status of SSRIs as first line agents in the pharmacotherapy of PTSD, as well as their value in long-term treatment, and suggest that long term medication may be required in treating PTSD.
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Smaller Hippocampal Volume in Posttraumatic Stress Disorder: A Multisite ENIGMA-PGC Study: Subcortical Volumetry Results From Posttraumatic Stress Disorder Consortia

Mark W. Logue, +55 more
TL;DR: This large-scale neuroimaging consortium study on PTSD conducted by the Psychiatric Genomics Consortium-Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA) PTSD Working Group represents an important milestone in an ongoing collaborative effort to examine the neurobiological underpinnings of PTSD and the brain's response to trauma.
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Genetic architecture of subcortical brain structures in 38,851 individuals

Claudia L. Satizabal, +375 more
- 21 Oct 2019 - 
TL;DR: This paper identified common genetic variation related to the volumes of the nucleus accumbens, amygdala, brainstem, caudate nucleus, globus pallidus, putamen and thalamus using genome-wide association analyses in almost 40,000 individuals from CHARGE, ENIGMA and UK Biobank.
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Evidence-based pharmacotherapy of post-traumatic stress disorder (PTSD).

TL;DR: The largest body of evidence for short- and long-term efficacy of medication currently exists for SSRIs, with promising initial findings for the selective noradrenergic reuptake inhibitor venlafaxine and the atypical antipsychotic risperidone.
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Pharmacological interventions for preventing post‐traumatic stress disorder (PTSD)

TL;DR: None of the single trials of escitalopram, temazepam and gabapentin demonstrated evidence that medication was superior to placebo in preventing the onset of PTSD.