S
Satori A. Marchitti
Researcher at United States Environmental Protection Agency
Publications - 23
Citations - 1694
Satori A. Marchitti is an academic researcher from United States Environmental Protection Agency. The author has contributed to research in topics: Aldehyde dehydrogenase & Breast milk. The author has an hindex of 15, co-authored 21 publications receiving 1426 citations. Previous affiliations of Satori A. Marchitti include University of Colorado Denver & Anschutz Medical Campus.
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Journal ArticleDOI
Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily.
TL;DR: What is currently known about each member of the human ALDH superfamily, composed of NAD(P)+-dependent enzymes that catalyze aldehyde oxidation, is presented including the pathophysiological significance of these enzymes.
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Neurotoxicity and Metabolism of the Catecholamine-Derived 3,4-Dihydroxyphenylacetaldehyde and 3,4-Dihydroxyphenylglycolaldehyde: The Role of Aldehyde Dehydrogenase
TL;DR: This article presents a comprehensive review of what is currently known of both the neurotoxicity and respective metabolism pathways of 3,4-dihydroxyphenylacetaldehyde and 3, 4-Dihydroxybutyric aciduria with an emphasis on the role that aldehyde dehydrogenase enzymes play in the detoxification of these two aldehydes.
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Metabolic Remodeling Induced by Mitochondrial Aldehyde Stress Stimulates Tolerance to Oxidative Stress in the Heart
Jin Endo,Motoaki Sano,Takaharu Katayama,Takako Hishiki,Ken Shinmura,Shintaro Morizane,Tomohiro Matsuhashi,Yoshinori Katsumata,Yan Zhang,Hideyuki Ito,Yoshiko Nagahata,Satori A. Marchitti,Kiyomi Nishimaki,Alexander M. Wolf,Hiroki Nakanishi,Fumiyuki Hattori,Vasilis Vasiliou,Takeshi Adachi,Ikuroh Ohsawa,Ryo Taguchi,Yoshio Hirabayashi,Shigeo Ohta,Makoto Suematsu,Satoshi Ogawa,Keiichi Fukuda +24 more
TL;DR: It is indicated that mitochondrial aldehyde stress in the heart induces metabolic remodeling, leading to activation of the glutathione–redox cycle, which confers resistance against acute oxidative stress induced by ischemia/reperfusion.
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Environmental Chemicals in Breast Milk and Formula: Exposure and Risk Assessment Implications.
Geniece M. Lehmann,Judy S. LaKind,Matthew H. Davis,Erin P. Hines,Satori A. Marchitti,Cecilia S. Alcala,Matthew Lorber +6 more
TL;DR: Better-designed studies are needed to characterize infant exposures to environmental chemicals in breast milk and infant formula as well as to improve risk assessments of chemicals found in both foods.
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Human and Rat ABC Transporter Efflux of Bisphenol A and Bisphenol A Glucuronide: Interspecies Comparison and Implications for Pharmacokinetic Assessment
Christopher S. Mazur,Satori A. Marchitti,Mira Dimova,John F. Kenneke,Annie Lumen,Jeffrey W. Fisher +5 more
TL;DR: Evaluated BPA and BPA-G as potential substrates for the human and rat ABC transporters: P-glycoprotein (MDR1), multidrug resistance-associated proteins (MRPs), and breast cancer-resistant protein (BCRP), and analysis of ABC transporter amino acid sequences revealed key differences in putative binding site composition that may explain substrate specificity.