S
Satoru Morita
Researcher at Keio University
Publications - 3
Citations - 680
Satoru Morita is an academic researcher from Keio University. The author has contributed to research in topics: Microbiome & Cytotoxic T cell. The author has an hindex of 3, co-authored 3 publications receiving 404 citations.
Papers
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Journal ArticleDOI
A defined commensal consortium elicits CD8 T cells and anti-cancer immunity
Takeshi Tanoue,Satoru Morita,Damian R. Plichta,Ashwin N. Skelly,Wataru Suda,Wataru Suda,Yuki Sugiura,Seiko Narushima,Hera Vlamakis,Iori Motoo,Kayoko Sugita,Atsushi Shiota,Kozue Takeshita,Keiko Yasuma-Mitobe,Dieter Riethmacher,Tsuneyasu Kaisho,Jason M. Norman,Daniel Mucida,Makoto Suematsu,Tomonori Yaguchi,Vanni Bucci,Takashi Inoue,Yutaka Kawakami,Bernat Olle,Bruce L. Roberts,Masahira Hattori,Masahira Hattori,Ramnik J. Xavier,Ramnik J. Xavier,Koji Atarashi,Kenya Honda +30 more
TL;DR: A consortium of 11 bacterial strains from the healthy human gut microbiota can strongly induce interferon-γ-producing CD8 T cells in the intestine, and enhance both resistance to bacterial infection and the therapeutic efficacy of immune checkpoint inhibitors in syngeneic tumour models.
Journal ArticleDOI
TH1 cell-inducing Escherichia coli strain identified from the small intestinal mucosa of patients with Crohn’s disease
Manabu Nagayama,Manabu Nagayama,Tomonori Yano,Koji Atarashi,Takeshi Tanoue,Mariko Sekiya,Yasutoshi Kobayashi,Hirotsugu Sakamoto,Kouichi Miura,Keijiro Sunada,Takaaki Kawaguchi,Satoru Morita,Kayoko Sugita,Seiko Narushima,Nicolas Barnich,Jun Isayama,Yuko Kiridooshi,Atsushi Shiota,Wataru Suda,Masahira Hattori,Hironori Yamamoto,Kenya Honda +21 more
TL;DR: The present results indicate that the CD SI mucosa harbors unique pro-inflammatory microbiota, including TH1 cell-inducing E. coli, which could be a potential therapeutic target.
Patent
Compositions and methods for the induction of cd8+ t-cells
TL;DR: In this paper, compositions and methods for the induction and/or proliferation of CD8+ T-cells are provided and methods of treatment of diseases that can be treated by the induction or proliferation of these cells.