Scott A. Read

TL;DR: This review summarizes current basic science and clinical evidence examining zinc as a direct antiviral, as well as a stimulant of antiviral immunity as a preventative and therapeutic treatment for viral infections.

TL;DR: This review will explore the unique mechanisms by which different oncogenic viruses induce inflammation to promote cancer initiation and progression.

TL;DR: Micronutrient deficiencies develop for a variety of reasons, whether geographic, socioeconomic, nutritional, or as a result of disease pathologies such as chronic viral infection, and their role in the pathogenesis of HCV infection and in the response to antiviral therapy is explored.

TL;DR: It is shown that the rs12979860 CC genotype correlates with increased hepatic metallothionein expression through increased systemic zinc levels, providing the first evidence that zinc can act as a potent and specific inhibitor of IFN-λ3 signalling and highlight its potential as a target of therapeutic intervention for IFN -λ3-mediated chronic disease.

TL;DR: It is demonstrated that macrophages are primary responders to IFN-λ, uniquely positioned to bridge the gap between IFn-λ producing cells and lymphocyte populations that are not intrinsically responsive to IFE, highlighting a novel role for macrophage in shaping IFN -λ dependent immune responses.