S
Scott A. Read
Researcher at University of Sydney
Publications - 41
Citations - 1107
Scott A. Read is an academic researcher from University of Sydney. The author has contributed to research in topics: Hepatitis C virus & Immune system. The author has an hindex of 14, co-authored 33 publications receiving 653 citations.
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Journal ArticleDOI
The Role of Zinc in Antiviral Immunity
TL;DR: This review summarizes current basic science and clinical evidence examining zinc as a direct antiviral, as well as a stimulant of antiviral immunity as a preventative and therapeutic treatment for viral infections.
Journal ArticleDOI
Virus induced inflammation and cancer development
Scott A. Read,Mark W. Douglas +1 more
TL;DR: This review will explore the unique mechanisms by which different oncogenic viruses induce inflammation to promote cancer initiation and progression.
Journal ArticleDOI
The role of micronutrients in the infection and subsequent response to hepatitis C virus
TL;DR: Micronutrient deficiencies develop for a variety of reasons, whether geographic, socioeconomic, nutritional, or as a result of disease pathologies such as chronic viral infection, and their role in the pathogenesis of HCV infection and in the response to antiviral therapy is explored.
Journal ArticleDOI
Zinc is a potent and specific inhibitor of IFN-λ3 signalling
Scott A. Read,Kate S. O'Connor,V. Suppiah,Chantelle L Ahlenstiel,Stephanie Obeid,Kristina M. Cook,Anthony L. Cunningham,Mark W. Douglas,Philip J. Hogg,David R. Booth,Jacob George,Golo Ahlenstiel +11 more
TL;DR: It is shown that the rs12979860 CC genotype correlates with increased hepatic metallothionein expression through increased systemic zinc levels, providing the first evidence that zinc can act as a potent and specific inhibitor of IFN-λ3 signalling and highlight its potential as a target of therapeutic intervention for IFN -λ3-mediated chronic disease.
Journal ArticleDOI
Macrophage Coordination of the Interferon Lambda Immune Response.
Scott A. Read,Ratna Sari Wijaya,Mehdi Ramezani-Moghadam,Enoch Tay,Steve Schibeci,Christopher Liddle,Vincent Lam,Vincent Lam,Lawrence Yuen,Lawrence Yuen,Mark W. Douglas,David R. Booth,Jacob George,Golo Ahlenstiel +13 more
TL;DR: It is demonstrated that macrophages are primary responders to IFN-λ, uniquely positioned to bridge the gap between IFn-λ producing cells and lymphocyte populations that are not intrinsically responsive to IFE, highlighting a novel role for macrophage in shaping IFN -λ dependent immune responses.