S
Scott A. Shuster
Researcher at Stanford University
Publications - 1
Citations - 130
Scott A. Shuster is an academic researcher from Stanford University. The author has contributed to research in topics: δ-opioid receptor & Somatosensory system. The author has an hindex of 1, co-authored 1 publications receiving 111 citations.
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Delta Opioid Receptors Presynaptically Regulate Cutaneous Mechanosensory Neuron Input to the Spinal Cord Dorsal Horn
Rita Bardoni,Vivianne L. Tawfik,Dong Wang,Amaury François,Carlos Solorzano,Scott A. Shuster,Papiya Choudhury,Chiara Betelli,Colleen Cassidy,Kristen Smith,Joriene C. de Nooij,Françoise Mennicken,Dajan O'Donnell,Brigitte L. Kieffer,C. Jeffrey Woodbury,Allan I. Basbaum,Amy B. MacDermott,Grégory Scherrer +17 more
TL;DR: It is demonstrated that DOR activation at the central terminals of myelinated mechanoreceptors depresses synaptic input to the spinal dorsal horn, via the inhibition of voltage-gated calcium channels, which reveals a molecular mechanism by which opioids modulate cutaneous mechanosensation.