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Scott D. Olson
Researcher at University of Texas Health Science Center at Houston
Publications - 70
Citations - 5232
Scott D. Olson is an academic researcher from University of Texas Health Science Center at Houston. The author has contributed to research in topics: Mesenchymal stem cell & Traumatic brain injury. The author has an hindex of 24, co-authored 56 publications receiving 4490 citations. Previous affiliations of Scott D. Olson include University of California, Davis & University of Texas at Austin.
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Mitochondrial transfer between cells can rescue aerobic respiration
TL;DR: It is reported here that mitochondria are more dynamic than previously considered: mitochondria or mtDNA can move between cells and the active transfer from adult stem cells and somatic cells can rescue aerobic respiration in mammalian cells with nonfunctional mitochondria.
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Multipotent stromal cells from human marrow home to and promote repair of pancreatic islets and renal glomeruli in diabetic NOD/scid mice
Ryang Hwa Lee,Min Jeong Seo,Roxanne L. Reger,Jeffrey L. Spees,Jeffrey L. Spees,Andrey A. Pulin,Scott D. Olson,Darwin J. Prockop +7 more
TL;DR: The results raised the possibility that hMSCs may be useful in enhancing insulin secretion and perhaps improving the renal lesions that develop in patients with diabetes mellitus.
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Differentiation, cell fusion, and nuclear fusion during ex vivo repair of epithelium by human adult stem cells from bone marrow stroma.
Jeffrey L. Spees,Scott D. Olson,Joni Ylostalo,Patrick J. Lynch,Jason Smith,Anthony Perry,Alexandra Peister,Meng Yu Wang,Darwin J. Prockop +8 more
TL;DR: To investigate stem cell differentiation in response to tissue injury, human mesenchymal stem cells were cocultured with heat-shocked small airway epithelial cells, and a subset of the hMSCs rapidly differentiated into epithelium-like cells and they restored the epithelial monolayer.
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Mesenchymal stem cells for the treatment of neurodegenerative disease
TL;DR: MSCs transplanted into the brain have been demonstrated to promote functional recovery by producing trophic factors that induce survival and regeneration of host neurons, and proposed regenerative approaches to neurological diseases using MSCs include cell therapies in which cells are delivered via intracerebral or intrathecal injection.
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Lactobacilli activate human dendritic cells that skew T cells toward T helper 1 polarization
Mansour Mohamadzadeh,Scott D. Olson,Warren V. Kalina,Gordon Ruthel,Gretchen L. Demmin,Kelly L. Warfield,Sina Bavari,Todd R. Klaenhammer +7 more
TL;DR: The results emphasize a potentially important role for lactobacilli in modulating immunological functions of DCs and suggest that certain strains could be particularly advantageous as vaccine adjuvants, by promoting DCs to regulate T cell responses toward T helper 1 and Tc1 pathways.