K
Kelly L. Warfield
Researcher at United States Department of the Army
Publications - 113
Citations - 6184
Kelly L. Warfield is an academic researcher from United States Department of the Army. The author has contributed to research in topics: Ebola virus & Virus. The author has an hindex of 46, co-authored 102 publications receiving 5669 citations. Previous affiliations of Kelly L. Warfield include United States Army Medical Research Institute of Infectious Diseases & National Institutes of Health.
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Journal ArticleDOI
Lactobacilli activate human dendritic cells that skew T cells toward T helper 1 polarization
Mansour Mohamadzadeh,Scott D. Olson,Warren V. Kalina,Gordon Ruthel,Gretchen L. Demmin,Kelly L. Warfield,Sina Bavari,Todd R. Klaenhammer +7 more
TL;DR: The results emphasize a potentially important role for lactobacilli in modulating immunological functions of DCs and suggest that certain strains could be particularly advantageous as vaccine adjuvants, by promoting DCs to regulate T cell responses toward T helper 1 and Tc1 pathways.
Journal ArticleDOI
Seasonal Pulses of Marburg Virus Circulation in Juvenile Rousettus aegyptiacus Bats Coincide with Periods of Increased Risk of Human Infection
Brian R. Amman,Serena A. Carroll,Zachary Reed,Tara K. Sealy,Stephen Balinandi,Robert Swanepoel,Alan Kemp,Bobbie R. Erickson,James A. Comer,Shelley Campbell,Deborah Cannon,Marina L. Khristova,Patrick Atimnedi,Christopher D. Paddock,Rebekah J. Kent Crockett,Timothy D. Flietstra,Kelly L. Warfield,Robert C. Unfer,Edward Katongole-Mbidde,Robert Downing,Jordan W. Tappero,Sherif R. Zaki,Pierre E. Rollin,Thomas G. Ksiazek,Stuart T. Nichol,Jonathan S. Towner +25 more
TL;DR: The discovery of two tags at Python Cave from bats marked at Kitaka mine, together with the close genetic linkages evident between viruses detected in geographically distant locations, are consistent with R. aegyptiacus bats existing as a large meta-population with associated virus circulation over broad geographic ranges.
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Ebola Virus-Like Particle-Based Vaccine Protects Nonhuman Primates against Lethal Ebola Virus Challenge
Kelly L. Warfield,Dana L. Swenson,Gene G. Olinger,Warren V. Kalina,M. Javad Aman,Sina Bavari +5 more
TL;DR: On the basis of safety and efficacy, eVLP-vaccinated monkeys survived challenge without clinical or laboratory signs of EBOV infection, whereas the control animal died of infection.
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Ebola virus-like particles protect from lethal Ebola virus infection
Kelly L. Warfield,Catharine M. Bosio,Brent C. Welcher,Emily M. Deal,Mansour Mohamadzadeh,Alan L. Schmaljohn,M. Javad Aman,Sina Bavari +7 more
TL;DR: It is reported that Ebola VLPs (eVLPs) were immunogenic in vitro as eVLPs matured and activated mouse bone marrow-derived dendritic cells, and mice vaccinated with eVDPs were 100% protected from an otherwise lethal Ebola virus inoculation.
Journal ArticleDOI
Rotavirus antigenaemia and viraemia: a common event?
Sarah E. Blutt,Carl D. Kirkwood,Viviana Parreño,Kelly L. Warfield,Max Ciarlet,Mary K. Estes,Karin Bok,Ruth F. Bishop,Margaret E. Conner,Margaret E. Conner +9 more
TL;DR: Rotavirus can escape the gastrointestinal tract in children, resulting in antigenaemia and possible viraemia, and this finding is important for the understanding of the pathogenesis, immunology, and clinical manifestations of rotavirus infection.