S
Seiji Suzuki
Researcher at University of Tsukuba
Publications - 46
Citations - 1492
Seiji Suzuki is an academic researcher from University of Tsukuba. The author has contributed to research in topics: Glucagon & Insulin. The author has an hindex of 19, co-authored 46 publications receiving 1442 citations.
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Journal ArticleDOI
Sterol Regulatory Element-Binding Proteins Induce an Entire Pathway of Cholesterol Synthesis
Yuki Sakakura,Hitoshi Shimano,Hirohito Sone,Akimitsu Takahashi,Kuniyuki Inoue,Hideyuki Toyoshima,Seiji Suzuki,Nobuhiro Yamada +7 more
TL;DR: It is demonstrated that SREBPs activate every step of cholesterol synthetic pathway, contributing to an efficient cholesterol synthesis.
Journal ArticleDOI
Eicosapentaenoic acid enhances nitric oxide production by cultured human endothelial cells.
Yukichi Okuda,Kazuko Kawashima,Toshie Sawada,Kazuki Tsurumaru,Michiko Asano,Seiji Suzuki,Masaaki Soma,Toshiaki Nakajima,Kamejiro Yamashita +8 more
TL;DR: Results suggest EPA-E might ameliorate endothelial dysfunction associated with diabetes by decreasing the glucose-mediated inhibition of NO production by HUE.
Journal ArticleDOI
Comparison of the effects of various C-terminal and N-terminal fragment peptides of glucagon-like peptide-1 on insulin and glucagon release from the isolated perfused rat pancreas
TL;DR: It is concluded that histidine at position 7 of GLP-1 as a free N-terminal amino acid is very important in GLp-1's insulinotropic activity and probably in glucagon-inhibiting activity, and that C- terminal amidation and three C-Terminal amino acids are less important for these activities.
Journal ArticleDOI
Comparison of the Effects of Glucagon-Like Peptide-1-( 1-3 7) and -(7-37) and Glucagon on Islet Hormone Release from Isolated Perfused Canine and Rat Pancreases*
Koichi Kawai,Seiji Suzuki,Shinichi Ohashi,Hidehito Mukai,Hajime Ohmori,Yasuko Murayama,Kamejiro Yamashita +6 more
TL;DR: The present results indicate that since GLP-1-(7-37) is released from the intestine, it might be an important incretin candidate along with gastric inhibitory peptide; and the release of proglucagon-derived peptides from pancreatic A-cells is regulated by autofeedback through glucagon and GLp-1.
Journal ArticleDOI
Long-term effects of eicosapentaenoic acid on diabetic peripheral neuropathy and serum lipids in patients with type II diabetes mellitus
Yukichi Okuda,Masakazu Mizutani,M. Ogawa,Hirohito Sone,Michiko Asano,Yukari Asakura,Masaaki Isaka,Seiji Suzuki,Yasushi Kawakami,James B. Field,James B. Field,Kamejiro Yamashita +11 more
TL;DR: It is suggested that EPA-E has significant beneficial effects on diabetic neuropathy and serum lipids as well as other diabetic complications such as nephropathy and macroangiopathy.