S
Sen Wang
Researcher at Nanjing Medical University
Publications - 38
Citations - 1851
Sen Wang is an academic researcher from Nanjing Medical University. The author has contributed to research in topics: Cancer & microRNA. The author has an hindex of 17, co-authored 30 publications receiving 1122 citations. Previous affiliations of Sen Wang include Yangzhou University.
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Journal ArticleDOI
Circular RNA circNRIP1 acts as a microRNA-149-5p sponge to promote gastric cancer progression via the AKT1/mTOR pathway
Xing Zhang,Sen Wang,Haixiao Wang,Jiacheng Cao,Xiaoxu Huang,Zheng Chen,Penghui Xu,Guangli Sun,Jianghao Xu,Jialun Lv,Zekuan Xu +10 more
TL;DR: It is proved that circNRIP1 sponges miR-149-5p to affect the expression level of AKT1 and eventually acts as a tumour promotor in GC and demonstrated that quaking can promote circ NRIP1 transcription.
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Circular RNA AKT3 upregulates PIK3R1 to enhance cisplatin resistance in gastric cancer via miR-198 suppression
Xiaoxu Huang,Xiaoxu Huang,Zheng Li,Qiang Zhang,Weizhi Wang,Bowen Li,Lu Wang,Zhipeng Xu,Ailiang Zeng,Xing Zhang,Xuan Zhang,Zhongyuan He,Qiang Li,Guangli Sun,Sen Wang,Qing Li,Linjun Wang,Lu Zhang,Hao Xu,Zekuan Xu +19 more
TL;DR: The data indicated that circAKT3 promotes DNA damage repair and inhibits the apoptosis of GC cells in vivo and in vitro and Mechanistically, it was verified that circ AKT3 could promote PIK3R1 expression by sponging miR-198.
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Cancer-associated fibroblasts promote angiogenesis in gastric cancer through galectin-1 expression.
Dong Tang,Jun Gao,Sen Wang,Nianyuan Ye,Yang Chong,Yuqin Huang,Jie Wang,Bin Li,Wei Yin,Daorong Wang +9 more
TL;DR: High expression of galectin-1 in the CAFs increased HUVEC proliferation, migration, tube formation, and VEGFR2 phosphorylation and enhanced VEGF expression in gastric cancer cells and may be a target for angiostatic therapy.
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A novel protein encoded by circMAPK1 inhibits progression of gastric cancer by suppressing activation of MAPK signaling.
Tianlu Jiang,Yiwen Xia,Jialun Lv,Bowen Li,Ying Li,Sen Wang,Zhe Xuan,Li Xie,Shengkui Qiu,Shengkui Qiu,Zhongyuan He,Linjun Wang,Zekuan Xu +12 more
TL;DR: It is revealed that circMAPK1 inhibits the malignant biological behavior of gastric cancer cells through its encoded protein MAPK1–109aa, which may provide a new therapeutic target in the treatment of Gastric cancer.
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Analysis of lncRNA-Associated ceRNA Network Reveals Potential lncRNA Biomarkers in Human Colon Adenocarcinoma
Zhiyuan Zhang,Wenwei Qian,Sen Wang,Dongjian Ji,Qingyuan Wang,Jie Li,Wen Peng,Jiou Gu,Tao Hu,Bing Ji,Yue Zhang,Shijia Wang,Yueming Sun +12 more
TL;DR: A ceRNA network of COAD-specific mRNAs, miRNAs and lncRNAs was constructed and showed that the potential mRNA targets of these 4 lnc RNAs may be concentrated in the MAPK pathway.