Guangli Sun

TL;DR: It is proved that circNRIP1 sponges miR-149-5p to affect the expression level of AKT1 and eventually acts as a tumour promotor in GC and demonstrated that quaking can promote circ NRIP1 transcription.

TL;DR: The data indicated that circAKT3 promotes DNA damage repair and inhibits the apoptosis of GC cells in vivo and in vitro and Mechanistically, it was verified that circ AKT3 could promote PIK3R1 expression by sponging miR-198.

TL;DR: In this paper, the authors performed integrated analysis of TCGA data from microRNAs (miRNAs) expression matrix of GC patients who received CDDP-based chemotherapy with GEO dataset which contains differential miRNAs expression profiles in CDDP resistant and -sensitive cell lines.

TL;DR: It is demonstrated that microRNA-133a-3p overexpression could block the activation of autophagy to ruin the abnormal glutaminolysis and further inhibit the growth and metastasis of gastric cancer cells.

TL;DR: The findings reveal that circOSBPL10 may serve as a new proliferation factor and prognostic marker in GC and that miR-136-5p is a downstream target of circOSbPL10 using RNA pull-down and luciferase reporter assays.