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Senhua Chen

Researcher at Sun Yat-sen University

Publications -  59
Citations -  1347

Senhua Chen is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 19, co-authored 51 publications receiving 858 citations. Previous affiliations of Senhua Chen include Chinese Ministry of Education.

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Isocoumarins and benzofurans from the mangrove endophytic fungus Talaromyces amestolkiae possess α-glucosidase inhibitory and antibacterial activities

TL;DR: Six new isocoumarins, compounds 1–4 and 14–15, two new benzofurans, 16–17, along with nine known isocOUmarin analogues, 5–13 were obtained from the mangrove endophytic fungus Talaromyces amestolkiae YX1 and their structures were elucidated by analysis of spectroscopic data.
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Aspterpenacids A and B, Two Sesterterpenoids from a Mangrove Endophytic Fungus Aspergillus terreus H010.

TL;DR: Two new sesterterpenoids, aspterpenacids A and B, with an unusual carbon skeleton of a 5/3/7/6/5 ring system were isolated from the mangrove endophytic fungus Aspergillus terreus H010 and showed no significant antibacterial activity or cytotoxicity at 50 μM.
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Cytotoxic and Antibacterial Preussomerins from the Mangrove Endophytic Fungus Lasiodiplodia theobromae ZJ-HQ1.

TL;DR: Two new chlorinated preussomersins, chloropreussomerins A and B (1 and 2), together with nine known preussomerin analogues, 3-11, were obtained from the endophytic fungus Lasiodiplodia theobromae ZJ-HQ1 and their structures were elucidated by a combination of spectroscopic analyses.
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Anti-inflammatory meroterpenoids from the mangrove endophytic fungus Talaromyces amestolkiae YX1.

TL;DR: Four previously undescribed meroterpenoids, amestolkolides A-D, along with three known compounds were isolated from the mangrove endophytic fungus Talaromyces amestoliae YX1 cultured on wheat solid-substrate medium culture and their structures were elucidated by a combination of spectroscopic analyses.
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Polyketides with Immunosuppressive Activities from Mangrove Endophytic Fungus Penicillium sp. ZJ-SY₂.

TL;DR: Nine polyketides, including two new benzophenone derivatives, peniphenone (1) and methyl penipenone (2), along with seven known xanthones (3–9) were obtained from mangrove endophytic fungus Penicillium sp.