There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality.

Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …

I and i

Probability Distributions.- Linear Models for Regression.- Linear Models for Classification.- Neural Networks.- Kernel Methods.- Sparse Kernel Machines.- Graphical Models.- Mixture Models and EM.- Approximate Inference.- Sampling Methods.- Continuous Latent Variables.- Sequential Data.- Combining Models.

Pattern Recognition and Machine Learning

CA : A Cancer Journal for Clinicians

Introduction to linear and nonlinear programming

Bilateral teleoperation: An historical survey

Liver fibrosis arises from chronic liver diseases, such as hepatitis B, C, and nonalcoholic steatohepatitis and can result in cirrhosis and death. Magnetic resonance elastography (MRE) is commonly regarded as the imaging-based gold-standard for fibrosis staging. With the aid of a state-of-the-art matrix array transducer, our previous 3D ultrasound shear wave absolute vibro-elastography (S-WAVE) imaging was able to generate hepatic stiffness measurements which are comparable to MRE. In this work, we introduce multi-frequency S-WAVE imaging with a matrix array transducer, to provide more robust and reliable measurements by shorter overall exam time. The system was characterized with three liver tissue phantoms of different elasticity using the MRE results as the ground truth. Six healthy volunteers and six patients who have chronic liver diseases were imaged. Our results indicate that measurements from multi-frequency 3D S-WAVE with a matrix array transducer correlated better to MRE, compared to the readings from the transient elastography method (FibroScan, Echosens).

In-Vivo Validation of 3D Multi-Frequency Liver Shear Wave Absolute Vibro-Elastography with an xMATRIX Array

This paper presents a numerical solution of the multiple objective control system design problem for SISO systems. An approximation for the free transfer function in the Q-parametrization, in terms of controller complexity, is proposed. Two examples are presented to show that the proposed method has the advantage of directly yielding low-order controllers.

Numerical solution of the multiple objective control system design problem for SISO systems

A semi-automatic segmentation method for prostate boundary delineation

We have integrated photoacoustic tomography into an automated breast ultrasound scanner. This system scans the patient in the prone position, so illuminating the breast required the development of a fiber-coupled illumination system and a light-shaping diffuser to direct the light onto the tissue. This system allows simultaneous acquisition of B-mode and multi-wavelength photoacoustic tomography data in a single, operator-independent scan. We present the first characterizations of this complete scanning system, as well as phantom data used to evaluate the attainable imaging depth, resolution, and sensitivity of the hardware and reconstruction scheme.

Septimiu E. Salcudean

Papers

In-Vivo Validation of 3D Multi-Frequency Liver Shear Wave Absolute Vibro-Elastography with an xMATRIX Array

Numerical solution of the multiple objective control system design problem for SISO systems

A semi-automatic segmentation method for prostate boundary delineation

Automated full-breast photoacoustic tomography with non-uniform illumination

3D prostate segmentation in TRUS images using image warping and ellipsoid fitting