S
Serge Eifes
Researcher at University of Luxembourg
Publications - 15
Citations - 1195
Serge Eifes is an academic researcher from University of Luxembourg. The author has contributed to research in topics: Curcumin & Gene. The author has an hindex of 11, co-authored 15 publications receiving 1093 citations.
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Modulation of anti-apoptotic and survival pathways by curcumin as a strategy to induce apoptosis in cancer cells
TL;DR: The main effects ofCurcumin on the different apoptotic signaling pathways involved in curcumin-induced apoptosis of cancer cells, including the intrinsic and extrinsic apoptosis pathways, the NF-kappaB-mediated pathway as well as the PI3K/Akt signaling pathway are reviewed.
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Integrating Pathways of Parkinson's Disease in a Molecular Interaction Map
Kazuhiro Fujita,Marek Ostaszewski,Yukiko Matsuoka,Samik Ghosh,Enrico Glaab,Christophe Trefois,Isaac Crespo,Thanneer M. Perumal,Wiktor Jurkowski,Paul Antony,Nico J. Diederich,Nico J. Diederich,Manuel Buttini,Akihiko Kodama,Venkata P. Satagopam,Serge Eifes,Antonio del Sol,Reinhard Schneider,Hiroaki Kitano,Rudi Balling +19 more
TL;DR: A computationally tractable, comprehensive molecular interaction map of Parkinson's disease that integrates pathways implicated in PD pathogenesis such as synaptic and mitochondrial dysfunction, impaired protein degradation, alpha-synuclein pathobiology and neuroinflammation is introduced.
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Curcumin―The Paradigm of a Multi-Target Natural Compound with Applications in Cancer Prevention and Treatment
TL;DR: How curcumin is able to modulate many components of intracellular signaling pathways implicated in inflammation, cell proliferation and invasion and to induce genetic modulations eventually leading to tumor cell death is summarized.
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Chemopreventive potential of curcumin in prostate cancer.
TL;DR: Curcumin appears thus as a non-toxic alternative for prostate cancer prevention, treatment or co-treatment, consistent with this compound’s ability to up-induce pro-APoptotic proteins and to down-regulate the anti-apoptotic counterparts.
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Heteronemin, a spongean sesterterpene, inhibits TNFα-induced NF-κB activation through proteasome inhibition and induces apoptotic cell death
Marc Schumacher,Claudia Cerella,Serge Eifes,Sébastien Chateauvieux,Franck Morceau,Marcel Jaspars,Mario Dicato,Marc Diederich +7 more
TL;DR: Results show that this compound has potential as anti-inflammatory and anti-cancer agent.