Rudi Balling

TL;DR: Analysis shows that Pax9 is a key regulator during the development of a wide range of organ primordia during mouse embryogenesis and in Pax9-deficient embryos tooth development is arrested at the bud stage.

TL;DR: It is shown that itaconic acid inhibits the growth of bacteria expressing isocitrate lyase, such as Salmonella enterica and Mycobacterium tuberculosis, and Irg1 gene silencing in macrophages resulted in significantly decreased intracellular itaconi acid levels as well as significantly reduced antimicrobial activity during bacterial infections.

TL;DR: In screening over 14,000 mice for a large number of clinically relevant parameters, 182 mouse mutants are recovered and this mutagenesis screen leads to a significant increase in the number of mouse models available to the scientific community.

TL;DR: It is shown that some families with WS have mutations in the human homologue9 of Pax-3, which is one of a family of eight Pax genes known in mice which are involved in regulating embryonic development and which contains a highly conserved transcription control sequence, the paired box.

TL;DR: A family of octamer‐binding proteins is present during mouse development and is differentially expressed during early embryogenesis, indicating that the female germline is targeted at later stages of germ cell development.