R
Reinhard Schneider
Researcher at University of Luxembourg
Publications - 342
Citations - 19582
Reinhard Schneider is an academic researcher from University of Luxembourg. The author has contributed to research in topics: Thin film & Transmission electron microscopy. The author has an hindex of 56, co-authored 324 publications receiving 17242 citations. Previous affiliations of Reinhard Schneider include Martin Luther University of Halle-Wittenberg & Technische Universität München.
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Journal ArticleDOI
Database of homology-derived protein structures and the structural meaning of sequence alignment.
Chris Sander,Reinhard Schneider +1 more
TL;DR: A database of homology‐derived secondary structure of proteins (HSSP) is produced by aligning to each protein of known structure all sequences deemed homologous on the basis of the threshold curve, effectively increasing the number of known protein structures by a factor of five to more than 1800.
Journal ArticleDOI
A series of PDB related databases for everyday needs.
Robbie P. Joosten,Tim A. H. te Beek,Elmar Krieger,Maarten L. Hekkelman,Rob Hooft,Reinhard Schneider,Chris Sander,Gert Vriend +7 more
TL;DR: A series of databases that run parallel to the Protein Data Bank, used for the analysis of properties of protein structures in areas ranging from structural genomics, to cancer biology and protein design, are presented.
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Correlated mutations and residue contacts in proteins.
TL;DR: A simple and general method is presented to analyze correlations in mutational behavior between different positions in a multiple sequence alignment to predict contact maps for each of 11 protein families and compare the result with the contacts determined by crystallography.
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Selection of representative protein data sets
TL;DR: Two algorithms are developed to extract from the data base representative sets of protein chains with maximum coverage and minimum redundancy and are generally applicable to other data bases in which criteria of similarity can be defined and relate to problems in graph theory.
Journal ArticleDOI
Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes
Beate Neumann,Thomas Walter,Jean-Karim Hériché,Jutta Bulkescher,Holger Erfle,Christian Conrad,Phill Rogers,Ina Poser,Michael Held,Urban Liebel,Cihan Cetin,Frank Sieckmann,Gregoire Pau,Rolf Kabbe,Annelie Wünsche,Venkata P. Satagopam,Michael H.A. Schmitz,Catherine Chapuis,Daniel W. Gerlich,Reinhard Schneider,Roland Eils,Wolfgang Huber,Jan-Michael Peters,Anthony A. Hyman,Richard Durbin,Rainer Pepperkok,Jan Ellenberg +26 more
TL;DR: This study carried out a genome-wide phenotypic profiling of each of the ∼21,000 human protein-coding genes by two-day live imaging of fluorescently labelled chromosomes, which allowed us to identify hundreds of human genes involved in diverse biological functions including cell division, migration and survival.