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Sergey N. Krylov
Researcher at York University
Publications - 228
Citations - 6908
Sergey N. Krylov is an academic researcher from York University. The author has contributed to research in topics: Capillary electrophoresis & Aptamer. The author has an hindex of 43, co-authored 219 publications receiving 6260 citations. Previous affiliations of Sergey N. Krylov include University of Birmingham & National Institutes of Health.
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Journal ArticleDOI
Nonequilibrium Capillary Electrophoresis of Equilibrium Mixtures: A Universal Tool for Development of Aptamers
Maxim V. Berezovski,Andrei P. Drabovich,Svetlana M. Krylova,Michael U. Musheev,Victor Okhonin,Alexander P. Petrov,Sergey N. Krylov +6 more
TL;DR: NECEEM-based selection has exceptionally high efficiency, which allows aptamer development with fewer rounds of selection, and can potentially facilitate selection of aptamers with predefined K(d), k(off), and k(on) of the aptamer-target interaction.
Journal ArticleDOI
Capillary Electrophoresis for the Analysis of Biopolymers
TL;DR: In this article, the authors present a review of the book.http://www.reviewreviews.com/reviews/book-reviews-of-the-book
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Non-SELEX Selection of Aptamers
TL;DR: For the first time, non-SELEX selection of aptamers is reported, a process that involves repetitive steps of partitioning with no amplification between them, and this work introduces an extremely fast and economical method for aptamer selection.
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A circular RNA circ-DNMT1 enhances breast cancer progression by activating autophagy
William W. Du,Weining Yang,Xiangmin Li,Faryal Mehwish Awan,Faryal Mehwish Awan,Zhenguo Yang,Ling Fang,Ling Fang,Juanjuan Lyu,Feiya Li,Chun Peng,Sergey N. Krylov,Yizhen Xie,Yaou Zhang,Chengyan He,Nan Wu,Chao Zhang,Mouna Sdiri,Jun Dong,Jian Ma,Chunqi Gao,Steven Hibberd,Burton B. Yang,Burton B. Yang +23 more
TL;DR: It is found that circ-Dnmt1-mediated autophagy was essential in inhibiting cellular senescence and increasing tumor xenograft growth, and the highly expressed circular RNA circ-Nmt1 could bind to and regulate oncogenic proteins in breast cancer cells.
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Aptamer-Facilitated Biomarker Discovery (AptaBiD)
TL;DR: AptaBiD was used to discover surface biomarkers that distinguish live mature and immature dendritic cells that were proven to be highly efficient in flow- and magnetic-bead-assisted separation of mature cells from immature cells.