Chun Peng

TL;DR: An update on canonical and non-canonical miRNA biogenesis pathways and various mechanisms underlying miRNA-mediated gene regulations and the current knowledge of the dynamics of miRNA action and of the secretion, transfer, and uptake of extracellular miRNAs is provided.

TL;DR: Results showed that miR-93 promotes tumor growth and angiogenesis by suppressing, at least in part, integrin-β8 expression, which is associated with cell death in tumor mass and in human glioblastoma.

TL;DR: Oxidative stress, the abnormal production and/or function of signaling molecules, as well as aberrant microRNAs expression have been suggested to participate in the pathogenesis of preeclampsia.

TL;DR: The present review summarizes the current knowledge on how endocrine and paracrine factors regulate ovarian development in zebrafish and special emphasis is placed on how follicle development and oocyte maturation in adult females is regulated by gonadotropins, ovarian steroids and growth factors produced by the ovary.

TL;DR: Results demonstrate for the first time that both GnRH and GnRHR mRNAs are expressed in human granulosa-luteal cells and GnRH gene expression is up-regulated by GnRH, but down- regulated by hCG, providing strong evidence that GnRH is an autocrine regulator in the human ovary.