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Shampa Chatterjee

Researcher at University of Pennsylvania

Publications -  97
Citations -  2989

Shampa Chatterjee is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: NADPH oxidase & Endothelial stem cell. The author has an hindex of 30, co-authored 89 publications receiving 2315 citations.

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Book ChapterDOI

Oxidative Stress, Inflammation, and Disease

TL;DR: The interrelation between oxidative stress and inflammation is discussed in the present chapter with a view to highlight the role of “ROS-induced-inflammation” pathways in the progression of several pathologies.
Journal ArticleDOI

Membrane depolarization is the trigger for PI3K/Akt activation and leads to the generation of ROS

TL;DR: It is indicated that PI3K/Akt and PKC serve as mediators between endothelial cell membrane depolarization and NOX2 assembly, and Akt1 phosphorylation follows cell membranes depolarized and precedes the activation of NOX 2.
Journal ArticleDOI

Peroxiredoxin 6 phosphorylation and subsequent phospholipase A2 activity are required for agonist-mediated activation of NADPH oxidase in mouse pulmonary microvascular endothelium and alveolar macrophages

TL;DR: It is demonstrated that Prdx6 is required for agonist-induced NOX2 activation in pulmonary microvascular endothelial cells (PMVEC) and that the effect requires the PLA2 activity of Prdx8, and that MAPK activation leads to Prx6 phosphorylation and translocation to the cell membrane.