S
Shau-Hua Ueng
Researcher at National Health Research Institutes
Publications - 40
Citations - 1917
Shau-Hua Ueng is an academic researcher from National Health Research Institutes. The author has contributed to research in topics: Boranes & Carbene. The author has an hindex of 19, co-authored 37 publications receiving 1699 citations. Previous affiliations of Shau-Hua Ueng include University of Pittsburgh & Centre national de la recherche scientifique.
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Journal ArticleDOI
N-Heterocyclic Carbene Boryl Radicals: A New Class of Boron-Centered Radical
Shau-Hua Ueng,Andrey Solovyev,Xinting Yuan,Steven J Geib,Louis Fensterbank,Emmanuel Lacôte,Max Malacria,Martin Newcomb,John C. Walton,Dennis P. Curran +9 more
TL;DR: These are the first NHC-boranes with boron-sulfur bonds, and their structures have been secured by spectroscopic and crystallographic means and Spectral analysis suggests that it is a pi-radical analogous to the benzyl radical.
Journal ArticleDOI
Complexes of Borane and N-Heterocyclic Carbenes: A New Class of Radical Hydrogen Atom Donor
Shau-Hua Ueng,Malika Makhlouf Brahmi,Etienne Derat,Louis Fensterbank,Emmanuel Lacôte,Max Malacria,Dennis P. Curran +6 more
TL;DR: The resulting prediction that NHC borane complexes could be used as radical hydrogen atom donors was verified by radical deoxygenations of xanthates by using either AIBN or triethylborane as initiator.
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EPR Studies of the Generation, Structure, and Reactivity of N-Heterocyclic Carbene Borane Radicals
John C. Walton,Malika Makhlouf Brahmi,Louis Fensterbank,Emmanuel Lacôte,Max Malacria,Qianli Chu,Shau-Hua Ueng,Andrey Solovyev,Dennis P. Curran +8 more
TL;DR: Spectroscopic data and DFT computations demonstrated that the NHC-BH(2)* radicals are planar pi-delocalized species, which is well suited for their reactivity to be tuned by inclusion of different NHC ring units and by appropriate placement of diverse substituents.
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Site-Specific Protein Modification through CuI-Catalyzed 1,2,3-Triazole Formation and Its Implementation in Protein Microarray Fabrication†
Po-Chiao Lin,Po-Chiao Lin,Shau-Hua Ueng,Mei-Chun Tseng,Jia-Ling Ko,Jia-Ling Ko,Kuo-Ting Huang,Sheng-Chieh Yu,Avijit K. Adak,Yu-Ju Chen,Yu-Ju Chen,Chun-Cheng Lin,Chun-Cheng Lin +12 more
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Important Hydrogen Bond Networks in Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Design Revealed by Crystal Structures of Imidazoleisoindole Derivatives with IDO1
Yi-Hui Peng,Shau-Hua Ueng,Chen-Tso Tseng,Ming-Shiu Hung,Jen-Shin Song,Jian-Sung Wu,Fang-Yu Liao,Yu-Shiou Fan,Mine-Hsine Wu,Wen-Chi Hsiao,Ching-Cheng Hsueh,Shu Yu Lin,Chia-Yi Cheng,Chih-Hsiang Tu,Lung-Chun Lee,Ming-Fu Cheng,Kak-Shan Shia,Chuan Shih,Su-Ying Wu +18 more
TL;DR: This study presents the structure of IDO1 in complex with 24, a NLG919 analogue with potent activity and demonstrates that extensive hydrophobic interactions and the unique hydrogen bonding network contribute to the great potency of imidazoleisoindole derivatives.