S
Shaun V. Walsh
Researcher at Ninewells Hospital
Publications - 45
Citations - 4685
Shaun V. Walsh is an academic researcher from Ninewells Hospital. The author has contributed to research in topics: Tight junction & Occludin. The author has an hindex of 25, co-authored 45 publications receiving 4234 citations. Previous affiliations of Shaun V. Walsh include Beth Israel Deaconess Medical Center & Emory University.
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Journal ArticleDOI
Synbiotic therapy (Bifidobacterium longum/Synergy 1) initiates resolution of inflammation in patients with active ulcerative colitis: a randomised controlled pilot trial
Elizabeth Furrie,Sandra Macfarlane,Aileen Kennedy,John H. Cummings,Shaun V. Walsh,O'neil Da,George T. Macfarlane +6 more
TL;DR: Short term synbiotic treatment of active UC resulted in improvement of the full clinical appearance of chronic inflammation in patients receiving this therapy.
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Human junction adhesion molecule regulates tight junction resealing in epithelia.
Yuan Liu,Asma Nusrat,Frederick J. Schnell,Titus A. Reaves,Shaun V. Walsh,Mildred Pochet,Charles A. Parkos +6 more
TL;DR: It is suggested that JAM plays an important role in the regulation of tight junction assembly in epithelia, and these JAM-mediated effects may occur by either direct, or indirect interactions with occludin.
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Matrix Stiffness Modulates Proliferation, Chemotherapeutic Response and Dormancy in Hepatocellular Carcinoma Cells
Joerg Schrader,Joerg Schrader,Timothy T. Gordon-Walker,Rebecca L. Aucott,Marielle Van Deemter,Alexander Quaas,Shaun V. Walsh,Daniel Benten,Stuart J. Forbes,Rebecca G. Wells,John P. Iredale +10 more
TL;DR: increasing matrix stiffness promotes proliferation and chemotherapeutic resistance, whereas a soft environment induces reversible cellular dormancy and stem cell characteristics in HCC, which has implications for both the treatment of primary HCC and the prevention of tumor outgrowth from disseminated tumor cells.
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Neutrophil transmigration in inflammatory bowel disease is associated with differential expression of epithelial intercellular junction proteins
TL;DR: Examination of expression of TJ and adherens junction proteins in relation to PMN infiltration in mucosal tissue samples from patients with active IBD suggests down-regulation of epithelial occludin may play a role in enhanced paracellular permeability and PMN transmigration that is observed in active inflammatory bowel disease.
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Allergic esophagitis in children: a clinicopathological entity.
Shaun V. Walsh,Donald A. Antonioli,Harvey Goldman,Victor L. Fox,Athos Bousvaros,Alan M. Leichtner,Glenn T. Furuta +6 more
TL;DR: A group of pediatric patients characterized by an allergic history, lack of adequate response to GERD therapy, normal esophageal pH probe monitoring results, and large numbers of eosinophils in esphageal biopsy specimens obtained after GERD treatment are proposed to represent examples of allergic esophagitis.