S
Sheu Ran Choi
Researcher at Seoul National University
Publications - 27
Citations - 631
Sheu Ran Choi is an academic researcher from Seoul National University. The author has contributed to research in topics: Neuropathic pain & Astrocyte. The author has an hindex of 14, co-authored 27 publications receiving 522 citations.
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Journal ArticleDOI
Acid evoked thermal hyperalgesia involves peripheral P2Y1 receptor mediated TRPV1 phosphorylation in a rodent model of thrombus induced ischemic pain.
Soon Gu Kwon,Dae Hyun Roh,Seo Yeon Yoon,Jiyoung Moon,Sheu Ran Choi,Hoon Seong Choi,Suk Yun Kang,Ho Jae Han,Alvin J. Beitz,Seog B. Oh,Jang Hern Lee +10 more
TL;DR: In this article, a thrombus-induced ischemic pain (TIIP) animal model was developed, which was characterized by chronic bilateral mechanical allodynia without thermal hyperalgesia (TH).
Acid evoked thermal hyperalgesia involves peripheral P2Y1 receptor mediated TRPV1 phosphorylation in a rodent model of thrombus
Soon Gu Kwon,Dae Hyun Roh,Seo-Yeon Yoon,Jiyoung Moon,Sheu Ran Choi,Hoon-Seong Choi,Suk-Yun Kang,Ho Jae Han,Alvin J. Beitz,Seog Bae Oh,Jang Hern Lee +10 more
TL;DR: In this article, a thrombus-induced ischemic pain (TIIP) animal model was developed, which was characterized by chronic bilateral mechanical allodynia without thermal hyperalgesia (TH).
Journal ArticleDOI
Neuronal NOS Activates Spinal NADPH Oxidase 2 Contributing to Central Sigma-1 Receptor-Induced Pain Hypersensitivity in Mice.
TL;DR: Findings demonstrate that spinal Sig-1R-induced pain hypersensitivity is mediated by nNOS activation, which leads to an increase in Nox2 activity ultimately resulting in a ROS-induced increase in PKC-dependent pGluN1 expression.
Journal ArticleDOI
Acidic pH facilitates peripheral αβmeATP-mediated nociception in rats: differential roles of P2X, P2Y, ASIC and TRPV1 receptors in ATP-induced mechanical allodynia and thermal hyperalgesia.
Hyoung Sig Seo,Dae Hyun Roh,Soon Gu Kwon,Seo Yeon Yoon,Suk Yun Kang,Jiyoung Moon,Sheu Ran Choi,Alvin J. Beitz,Jang Hern Lee +8 more
TL;DR: It is demonstrated that low tissue pH facilitates ATP-mediated MA via the activation of P2X receptors and ASICs, whereas TH induced by ATP under low pH conditions is mediated by the P2Y1 receptor and TRPV1, but not ASIC.
Journal ArticleDOI
Role of peripheral sigma-1 receptors in ischaemic pain: Potential interactions with ASIC and P2X receptors
Soon Gu Kwon,Dae Hyun Roh,Seo-Yeon Yoon,Seo-Yeon Yoon,Sheu Ran Choi,Hoon Seong Choi,Jiyoung Moon,S. Y. Kang,Hyun-Woo Kim,Ho Jae Han,Al J Beitz,Seog Bae Oh,Seog Bae Oh,Jang Hern Lee +13 more
TL;DR: The role of Sig‐1Rs in ischaemia‐induced mechanical allodynia (MA) is investigated and their possible interaction with acid‐sensing ion channels (ASICs) and P2X receptors at the ischaemic site is addressed.