S
Shigehiko Uni
Researcher at University of Malaya
Publications - 90
Citations - 2925
Shigehiko Uni is an academic researcher from University of Malaya. The author has contributed to research in topics: Onchocerca & Plasmodium falciparum. The author has an hindex of 28, co-authored 87 publications receiving 2730 citations. Previous affiliations of Shigehiko Uni include Kobe Women's University & French Institute of Health and Medical Research.
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Journal ArticleDOI
Secretion of a malarial histidine-rich protein (Pf HRP II) from Plasmodium falciparum-infected erythrocytes
Russell J. Howard,Shigehiko Uni,Masamichi Aikawa,Stephen B. Aley,J H Leech,Andrew M. Lew,Thomas E. Wellems,J Rener,D W Taylor +8 more
TL;DR: Results provide evidence for an intracellular route of transport for a secreted malarial protein from the parasite through several membranes and the host cell cytoplasm.
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Integrated taxonomy: traditional approach and DNA barcoding for the identification of filarioid worms and related parasites (Nematoda)
Emanuele Ferri,Michela Barbuto,Odile Bain,Andrea Galimberti,Shigehiko Uni,Ricardo Guerrero,Hubert Ferté,Claudio Bandi,Coralie Martin,Maurizio Casiraghi +9 more
TL;DR: DNA barcoding is proposed as a reliable, consistent, and democratic tool for species discrimination in routine identification of parasitic nematodes and the coherence between DNA-based and morphological identification for almost all the species examined is very strong.
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New insights into the evolution of Wolbachia infections in filarial nematodes inferred from a large range of screened species.
Emanuele Ferri,Odile Bain,Michela Barbuto,Coralie Martin,Nathan Lo,Shigehiko Uni,Frédéric Landmann,Sara G. Baccei,Ricardo Guerrero,Sueli de Souza Lima,Claudio Bandi,Samuel Wanji,M. Diagne,Maurizio Casiraghi +13 more
TL;DR: The absence of Wolbachia in 63% of onchocercids, notably in the ancestral Oswaldofilariinae estimated 140 mya old, the diverse tissues or specimens distribution, and a recent lateral transfer in supergroup F WolbachIA modify the current view on the role and evolution of the endosymbiont and their hosts.
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Immune responses to Cryptosporidium muris and Cryptosporidium parvum in adult immunocompetent or immunocompromised (nude and SCID) mice.
TL;DR: The results suggested that the two animal models should be valuable in the study of immunity to cryptosporidial infection.
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Localization of Plasmodium falciparum histidine-rich protein 1 in the erythrocyte skeleton under knobs.
Diane Wallace Taylor,Marcela Parra,George B. Chapman,Mark E. Stearns,Joan Rener,Masamichi Aikawa,Shigehiko Uni,Stephen B. Aley,Lindsey J. Panton,Russell J. Howard +9 more
TL;DR: Immunofluorescence and immunoelectron microscopy of intact, non-fixed K+ infected erythrocytes using mAb 89 and a rabbit antiserum raised against purified PfHRP-1, failed to identify any surface exposed epitopes.